EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
2.6.1.64 | Homo sapiens | - |
recombinant | - |
4.4.1.13 | Homo sapiens | - |
- |
- |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
4.4.1.13 | kidney | - |
Homo sapiens | - |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.6.1.64 | 5-S-L-cysteinyl-L-DOPA + 4-(methylsulfanyl)-2-oxobutanoate | - |
Homo sapiens | ? | - |
? | |
2.6.1.64 | 5-S-L-cysteinyldopamine + 4-(methylsulfanyl)-2-oxobutanoate | transamination of 5 mM 5-S-Lcysteinyldopamine with 1 mM 4-(methylsulfanyl)-2-oxobutanoateat pH 7.4 is about 0.07% the rate at which the enzyme catalyzes transamination between 20 mM L-phenylalanine and 5 mM alpha-oxo-gamma-methiolbutyrate | Homo sapiens | ? | - |
? | |
2.6.1.64 | L-3-(1-naphthyl)alanine + 4-(methylsulfanyl)-2-oxobutanoate | about 0.2% the rate exhibited with L-phenylalanine and alpha-oxo-gamma-methiolbutyrate | Homo sapiens | ? | - |
? | |
2.6.1.64 | L-3-(2-naphthyl)alanine + 4-(methylsulfanyl)-2-oxobutanoate | about 0.5% the rate exhibited with L-phenylalanine and alpha-oxo-gamma-methiolbutyrate | Homo sapiens | ? | - |
? | |
2.6.1.64 | L-DOPA + 4-(methylsulfanyl)-2-oxobutanoate | about 0.02% the rate exhibited with L-phenylalanine and alpha-oxo-gamma-methiolbutyrate | Homo sapiens | ? | - |
? | |
2.6.1.64 | L-kynurenine + 4-(methylsulfanyl)-2-oxobutanoate | about 23.6% the rate exhibited with L-phenylalanine and alpha-oxo-gamma-methiolbutyrate | Homo sapiens | ? | - |
? | |
2.6.1.64 | L-phenylalanine + 4-(methylsulfanyl)-2-oxobutanoate | - |
Homo sapiens | ? | - |
? | |
2.6.1.64 | L-tyrosine + 4-(methylsulfanyl)-2-oxobutanoate | about 9% the rate exhibited with L-phenylalanine and alpha-oxo-gamma-methiolbutyrate | Homo sapiens | ? | - |
? | |
2.6.1.64 | additional information | recombinant human glutamine transaminase K exhibits broad specificity both as an aminotransferase and as a cysteine S-conjugate beta-lyase | Homo sapiens | ? | - |
? | |
2.6.1.64 | phenylpyruvate + L-glutamine | about 64% the rate exhibited with L-phenylalanine and alpha-oxo-gamma-methiolbutyrate | Homo sapiens | ? | - |
? | |
2.6.1.64 | phenylpyruvate + L-leucine | about 25% the rate exhibited with L-phenylalanine and alpha-oxo-gamma-methiolbutyrate | Homo sapiens | ? | - |
? | |
2.6.1.64 | phenylpyruvate + L-methionine | about 30% the rate exhibited with L-phenylalanine and alpha-oxo-gamma-methiolbutyrate | Homo sapiens | ? | - |
? | |
2.6.1.64 | S-(1,1,2,2-tetrafluoroethyl)-L-cysteine + 4-(methylsulfanyl)-2-oxobutanoate | about 63% the rate exhibited with L-phenylalanine and alpha-oxo-gamma-methiolbutyrate | Homo sapiens | ? | - |
? | |
2.6.1.64 | S-(1,2-dichlorovinyl)-L-cysteine + 4-(methylsulfanyl)-2-oxobutanoate | about 13% the rate exhibited with L-phenylalanine and alpha-oxo-gamma-methiolbutyrate | Homo sapiens | ? | - |
? | |
2.6.1.64 | Se-methyl-L-selenocysteine + 4-(methylsulfanyl)-2-oxobutanoate | - |
Homo sapiens | ? | - |
? | |
4.4.1.13 | 5-S-L-cysteinyldopamine | slow beta-elimination reaction | Homo sapiens | pyruvate + ? | - |
? | |
4.4.1.13 | benzothiazolyl-L-cysteine | - |
Homo sapiens | ? | - |
? | |
4.4.1.13 | beta-chloro-DL-alanine | - |
Homo sapiens | ? | - |
? | |
4.4.1.13 | additional information | beta-lyase reactions with S-(1,1,2,2-tetrafluoroethyl)-L-cysteine, S-(1,2-dichlorovinyl)-L-cysteine, and Se-methyl-L-selenocysteine are more favorable than the GTK-catalyzed aminotransferase reactions with these amino acids | Homo sapiens | ? | - |
? | |
4.4.1.13 | additional information | no reaction with 5-S-L-cysteinyl-L-DOPA | Homo sapiens | ? | - |
? | |
4.4.1.13 | RSH-CH2-CH(NH3+)COO- + H2O | - |
Homo sapiens | RSH + NH3 + pyruvate | - |
? | |
4.4.1.13 | S-(1,1,2,2-tetrafluoroethyl)-L-cysteine | - |
Homo sapiens | NH3 + pyruvate + 1,1,2,2-tetrafluoroethanethiol | - |
? | |
4.4.1.13 | S-(1,2-dichlorovinyl)-L-cysteine | - |
Homo sapiens | ? | - |
? | |
4.4.1.13 | Se-methyl-L-selenocysteine | - |
Homo sapiens | ? | - |
? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
2.6.1.64 | glutamine transaminase K | - |
Homo sapiens |
2.6.1.64 | GTK | - |
Homo sapiens |
4.4.1.13 | beta-lyase | - |
Homo sapiens |
4.4.1.13 | glutamine transaminase K | exhibits broad specificity both as an aminotransferase and as a cysteine S-conjugate beta-lyase | Homo sapiens |
4.4.1.13 | GTK | - |
Homo sapiens |
EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|---|
2.6.1.64 | 9 | - |
- |
Homo sapiens |
EC Number | Cofactor | Comment | Organism | Structure |
---|---|---|---|---|
4.4.1.13 | pyridoxal 5'-phosphate | - |
Homo sapiens |