Literature summary extracted from

Boccia, S.; Hung, R.; Ricciardi, G.; Gianfagna, F.; Ebert, M.P.; Fang, J.Y.; Gao, C.M.; Goetze, T.; Graziano, F.; Lacasana-Navarro, M.; Lin, D.; Lopez-Carrillo, L.; Qiao, Y.L.; Shen, H.; Stolzenberg-Solomon, R.; Takezaki, T.; Weng, Y.R.; Zhang, F.F.; van Duijn, C.M.; Boffetta, P.; Taioli, E.
Meta- and pooled analyses of the methylenetetrahydrofolate reductase C677T and A1298C polymorphisms and gastric cancer risk: a huge-GSEC review (2008), Am. J. Epidemiol., 167, 505-516.

Protein Variants

EC Number	Protein Variants	Comment	Organism
1.5.1.20	additional information	gastric cancer risk is associated with C677T bit not A1298C gene polymorphism	Homo sapiens

EC Number	Organism	UniProt	Comment	Textmining
1.5.1.20	Homo sapiens	-	-	-

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
1.5.1.20	5,10-methylenetetrahydrofolate + acceptor	-	Homo sapiens	5-methyltetrahydrofolate + reduced acceptor	-	ir

EC Number	Synonyms	Comment	Organism
1.5.1.20	methylenetetrahydrofolate reductase	-	Homo sapiens
1.5.1.20	MTHFR	-	Homo sapiens

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Release 2023.1 (January 2023)