BRENDA - Enzyme Database

Molecular cloning, expression and characterization of ribokinase of Leishmania major

Ogbunude, P.O.; Lamour, N.; Barrett, M.P.; Acta Biochim. Biophys. Sin. (Shanghai) 39, 462-466 (2007)

Data extracted from this reference:

Cloned(Commentary)
EC Number
Commentary
Organism
2.7.1.15
overexpression in Escherichia coli
Leishmania major
Inhibitors
EC Number
Inhibitors
Commentary
Organism
Structure
2.7.1.15
D-ribose 5-phosphate
inhibits the phosphorylation of D-ribose
Leishmania major
KM Value [mM]
EC Number
KM Value [mM]
KM Value Maximum [mM]
Substrate
Commentary
Organism
Structure
2.7.1.15
0.2
-
ATP
-
Leishmania major
2.7.1.15
0.3
-
D-ribose
-
Leishmania major
Organism
EC Number
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
2.7.1.15
Leishmania major
-
-
-
Substrates and Products (Substrate)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
2.7.1.15
ATP + D-ribose
-
684118
Leishmania major
ADP + D-ribose 5-phosphate
-
-
-
?
Turnover Number [1/s]
EC Number
Turnover Number Minimum [1/s]
Turnover Number Maximum [1/s]
Substrate
Commentary
Organism
Structure
2.7.1.15
10.2
-
ATP
-
Leishmania major
2.7.1.15
10.8
-
D-ribose
-
Leishmania major
Ki Value [mM]
EC Number
Ki Value [mM]
Ki Value maximum [mM]
Inhibitor
Commentary
Organism
Structure
2.7.1.15
0.4
-
D-ribose 5-phosphate
-
Leishmania major
Cloned(Commentary) (protein specific)
EC Number
Commentary
Organism
2.7.1.15
overexpression in Escherichia coli
Leishmania major
Inhibitors (protein specific)
EC Number
Inhibitors
Commentary
Organism
Structure
2.7.1.15
D-ribose 5-phosphate
inhibits the phosphorylation of D-ribose
Leishmania major
Ki Value [mM] (protein specific)
EC Number
Ki Value [mM]
Ki Value maximum [mM]
Inhibitor
Commentary
Organism
Structure
2.7.1.15
0.4
-
D-ribose 5-phosphate
-
Leishmania major
KM Value [mM] (protein specific)
EC Number
KM Value [mM]
KM Value Maximum [mM]
Substrate
Commentary
Organism
Structure
2.7.1.15
0.2
-
ATP
-
Leishmania major
2.7.1.15
0.3
-
D-ribose
-
Leishmania major
Substrates and Products (Substrate) (protein specific)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
2.7.1.15
ATP + D-ribose
-
684118
Leishmania major
ADP + D-ribose 5-phosphate
-
-
-
?
Turnover Number [1/s] (protein specific)
EC Number
Turnover Number Minimum [1/s]
Turnover Number Maximum [1/s]
Substrate
Commentary
Organism
Structure
2.7.1.15
10.2
-
ATP
-
Leishmania major
2.7.1.15
10.8
-
D-ribose
-
Leishmania major