Reference Id = 682957 - BRENDA Enzyme Database

Inhibitors

EC Number	Inhibitors	Comment	Organism
4.1.2.27	2-acetyl-4-tetrahydroxybutylimidazole	-	Caenorhabditis elegans
4.1.2.27	2-acetyl-4-tetrahydroxybutylimidazole	-	Drosophila melanogaster
4.1.2.27	2-acetyl-4-tetrahydroxybutylimidazole	-	Homo sapiens
4.1.2.27	2-acetyl-4-tetrahydroxybutylimidazole	-	Mus musculus
4.1.2.27	2-acetyl-4-tetrahydroxybutylimidazole	-	Rattus norvegicus
4.1.2.27	bisulfite	-	Caenorhabditis elegans
4.1.2.27	bisulfite	-	Drosophila melanogaster
4.1.2.27	bisulfite	-	Homo sapiens
4.1.2.27	bisulfite	-	Mus musculus
4.1.2.27	bisulfite	-	Rattus norvegicus
4.1.2.27	cyanide	-	Caenorhabditis elegans
4.1.2.27	cyanide	-	Drosophila melanogaster
4.1.2.27	cyanide	-	Homo sapiens
4.1.2.27	cyanide	-	Mus musculus
4.1.2.27	cyanide	-	Rattus norvegicus
4.1.2.27	cysteine	-	Caenorhabditis elegans
4.1.2.27	cysteine	-	Drosophila melanogaster
4.1.2.27	cysteine	-	Homo sapiens
4.1.2.27	cysteine	-	Mus musculus
4.1.2.27	cysteine	-	Rattus norvegicus
4.1.2.27	deoxypyridoxine	competitive inhibitor	Caenorhabditis elegans
4.1.2.27	deoxypyridoxine	competitive inhibitor	Drosophila melanogaster
4.1.2.27	deoxypyridoxine	competitive inhibitor	Homo sapiens
4.1.2.27	deoxypyridoxine	competitive inhibitor	Mus musculus
4.1.2.27	deoxypyridoxine	competitive inhibitor	Rattus norvegicus
4.1.2.27	FTY720	-	Caenorhabditis elegans
4.1.2.27	FTY720	-	Drosophila melanogaster
4.1.2.27	FTY720	-	Homo sapiens
4.1.2.27	FTY720	-	Mus musculus
4.1.2.27	FTY720	-	Rattus norvegicus
4.1.2.27	Semicarbazide	-	Caenorhabditis elegans
4.1.2.27	Semicarbazide	-	Drosophila melanogaster
4.1.2.27	Semicarbazide	-	Homo sapiens
4.1.2.27	Semicarbazide	-	Mus musculus
4.1.2.27	Semicarbazide	-	Rattus norvegicus

Localization

EC Number	Localization	Comment	Organism	GeneOntology No.	Textmining
4.1.2.27	endoplasmic reticulum	-	Drosophila melanogaster	5783	-
4.1.2.27	endoplasmic reticulum	-	Mus musculus	5783	-
4.1.2.27	endoplasmic reticulum	-	Homo sapiens	5783	-
4.1.2.27	endoplasmic reticulum	-	Rattus norvegicus	5783	-
4.1.2.27	endoplasmic reticulum	-	Caenorhabditis elegans	5783	-
4.1.2.27	microsome	-	Drosophila melanogaster	-	-
4.1.2.27	microsome	-	Mus musculus	-	-
4.1.2.27	microsome	-	Homo sapiens	-	-
4.1.2.27	microsome	-	Rattus norvegicus	-	-
4.1.2.27	microsome	-	Caenorhabditis elegans	-	-
4.1.2.27	mitochondrion	-	Drosophila melanogaster	5739	-
4.1.2.27	mitochondrion	-	Mus musculus	5739	-
4.1.2.27	mitochondrion	-	Homo sapiens	5739	-
4.1.2.27	mitochondrion	-	Rattus norvegicus	5739	-
4.1.2.27	mitochondrion	-	Caenorhabditis elegans	5739	-

Molecular Weight [Da]

EC Number	Molecular Weight [Da]	Molecular Weight Maximum [Da]	Comment	Organism
4.1.2.27	63500	-	SDS-PAGE	Homo sapiens

Organism

EC Number	Organism	UniProt	Comment	Textmining
4.1.2.27	Caenorhabditis elegans	-	-	-
4.1.2.27	Dictyostelium discoideum	-	-	-
4.1.2.27	Drosophila melanogaster	-	-	-
4.1.2.27	Homo sapiens	-	-	-
4.1.2.27	Leishmania major	-	-	-
4.1.2.27	Mus musculus	-	-	-
4.1.2.27	Rattus norvegicus	-	-	-

Source Tissue

EC Number	Source Tissue	Comment	Organism	Textmining
4.1.2.27	brain	-	Mus musculus	-
4.1.2.27	brain	-	Rattus norvegicus	-
4.1.2.27	colon	-	Mus musculus	-
4.1.2.27	colon	-	Rattus norvegicus	-
4.1.2.27	gut	-	Drosophila melanogaster	-
4.1.2.27	gut	-	Caenorhabditis elegans	-
4.1.2.27	heart	-	Mus musculus	-
4.1.2.27	heart	-	Rattus norvegicus	-
4.1.2.27	liver	-	Mus musculus	-
4.1.2.27	liver	-	Rattus norvegicus	-
4.1.2.27	lymphocyte	-	Homo sapiens	-
4.1.2.27	small intestine	-	Mus musculus	-
4.1.2.27	small intestine	-	Rattus norvegicus	-
4.1.2.27	thymus	-	Mus musculus	-
4.1.2.27	thymus	-	Homo sapiens	-
4.1.2.27	thymus	-	Rattus norvegicus	-

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.
4.1.2.27	sphingosine 1-phosphate	-	Drosophila melanogaster	phosphoethanolamine + palmitaldehyde	-	ir
4.1.2.27	sphingosine 1-phosphate	-	Mus musculus	phosphoethanolamine + palmitaldehyde	-	ir
4.1.2.27	sphingosine 1-phosphate	-	Rattus norvegicus	phosphoethanolamine + palmitaldehyde	-	ir
4.1.2.27	sphingosine 1-phosphate	-	Dictyostelium discoideum	phosphoethanolamine + palmitaldehyde	-	ir
4.1.2.27	sphingosine 1-phosphate	-	Caenorhabditis elegans	phosphoethanolamine + palmitaldehyde	-	ir
4.1.2.27	sphingosine 1-phosphate	-	Leishmania major	phosphoethanolamine + palmitaldehyde	-	ir

Synonyms

EC Number	Synonyms	Comment	Organism
4.1.2.27	sphingosine-1-phosphate lyase	-	Drosophila melanogaster
4.1.2.27	sphingosine-1-phosphate lyase	-	Mus musculus
4.1.2.27	sphingosine-1-phosphate lyase	-	Homo sapiens
4.1.2.27	sphingosine-1-phosphate lyase	-	Rattus norvegicus
4.1.2.27	sphingosine-1-phosphate lyase	-	Dictyostelium discoideum
4.1.2.27	sphingosine-1-phosphate lyase	-	Caenorhabditis elegans
4.1.2.27	sphingosine-1-phosphate lyase	-	Leishmania major
4.1.2.27	SPL	-	Drosophila melanogaster
4.1.2.27	SPL	-	Mus musculus
4.1.2.27	SPL	-	Homo sapiens
4.1.2.27	SPL	-	Rattus norvegicus
4.1.2.27	SPL	-	Dictyostelium discoideum
4.1.2.27	SPL	-	Caenorhabditis elegans
4.1.2.27	SPL	-	Leishmania major

Cofactor

EC Number	Cofactor	Comment	Organism
4.1.2.27	pyridoxal 5'-phosphate	-	Drosophila melanogaster
4.1.2.27	pyridoxal 5'-phosphate	-	Mus musculus
4.1.2.27	pyridoxal 5'-phosphate	-	Homo sapiens
4.1.2.27	pyridoxal 5'-phosphate	-	Rattus norvegicus
4.1.2.27	pyridoxal 5'-phosphate	-	Dictyostelium discoideum
4.1.2.27	pyridoxal 5'-phosphate	-	Caenorhabditis elegans
4.1.2.27	pyridoxal 5'-phosphate	-	Leishmania major

Literature summary extracted from

Inhibitors

Localization

Molecular Weight [Da]

Organism

Source Tissue

Substrates and Products (Substrate)

Synonyms

Cofactor