Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Koo, I.C.; Ohol, Y.M.; Wu, P.; Morisaki, J.H.; Cox, J.S.; Brown, E.J.
    Role for lysosomal enzyme beta-hexosaminidase in the control of mycobacteria infection (2008), Proc. Natl. Acad. Sci. USA, 105, 710-715.
    View publication on PubMedView publication on EuropePMC

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.2.1.52 additional information Drosophila melanogaster HEXO2 Is important for limiting growth of Mycobacterium marinum in S2 cells. HEXO2 isoform is sufficient to control bacterial growth in S2 cells ?
-
 ?
3.2.1.52 additional information Mus musculus HEXO2 Is important for limiting growth of Mycobacterium marinum in S2 cells. HEXO2 isoform is sufficient to control bacterial growth in S2 cells ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
3.2.1.52 Drosophila melanogaster
-
-
-
3.2.1.52 Mus musculus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.2.1.52 macrophage the importance of beta-hexosaminidase for restricting mycobacterial growth during mammalian infections is confirmed in macrophages from beta-hexosaminidase knockout mice. beta-Hexosaminidase is characterized as a peptidoglycan hydrolase that exerts its mycobactericidal effect at the macrophage plasma membrane during mycobacteria-induced secretion of lysosomes Mus musculus
-
3.2.1.52 S2 cell
-
 Drosophila melanogaster
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.2.1.52 additional information HEXO2 Is important for limiting growth of Mycobacterium marinum in S2 cells. HEXO2 isoform is sufficient to control bacterial growth in S2 cells Drosophila melanogaster ?
-
 ?
3.2.1.52 additional information HEXO2 Is important for limiting growth of Mycobacterium marinum in S2 cells. HEXO2 isoform is sufficient to control bacterial growth in S2 cells Mus musculus ?
-
 ?

Synonyms

EC Number Synonyms Comment Organism
3.2.1.52 beta-hexosaminidase
-
 Mus musculus
3.2.1.52 HEXO2
-
 Drosophila melanogaster