Literature summary extracted from

Wu, C.Y.; Lu, J.; Cao, Q.; Guo, C.H.; Gao, Q.; Ling, E.A.
Expression of 2,3-cyclic nucleotide 3-phosphodiesterase in the amoeboid microglial cells in the developing rat brain (2006), Neuroscience, 142, 333-341.

Activating Compound

EC Number	Activating Compound	Comment	Organism	Structure
3.1.4.37	lipopolysaccharide	enzyme expression is significantly up-regulated in microglial activation induced in vitro by lipopolysaccharide	Rattus norvegicus

Localization

EC Number	Localization	Comment	Organism	GeneOntology No.	Textmining
3.1.4.37	mitochondrion	-	Rattus norvegicus	5739	-
3.1.4.37	plasma membrane	-	Rattus norvegicus	5886	-

Organism

EC Number	Organism	UniProt	Comment	Textmining
3.1.4.37	Rattus norvegicus	-	-	-

Source Tissue

EC Number	Source Tissue	Comment	Organism	Textmining
3.1.4.37	brain	developing brain	Rattus norvegicus	-
3.1.4.37	cavum septum pellucidum	presence of enzyme immunoreactive material at birth, progressive reduction with age with complete loss at postnatal day 18	Rattus norvegicus	-
3.1.4.37	corpus callosum	presence of enzyme immunoreactive material at birth, progressive reduction with age with complete loss at postnatal day 18	Rattus norvegicus	-
3.1.4.37	microglia	-	Rattus norvegicus	-
3.1.4.37	subventricular zone	presence of enzyme immunoreactive material at birth, progressive reduction with age with complete loss at postnatal day 18	Rattus norvegicus	-

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Release 2023.1 (January 2023)