EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
4.2.1.3 | oxalomalic acid | inhibition of aconitase activity, leading to inhibition of L-glutamate production, L-cystine uptake, and decrease in glutathione concentration in lens epithelial cells and retinal pigment epithelial cells | Canis lupus familiaris |
EC Number | Metals/Ions | Comment | Organism | Structure |
---|---|---|---|---|
4.2.1.3 | Iron | iron-induced increase in L-glutamate availability increases via the aconitase pathway L-cystine uptake, with subsequent increases in glutathione levels | Canis lupus familiaris |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
4.2.1.3 | Canis lupus familiaris | - |
- |
- |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
4.2.1.3 | eye | - |
Canis lupus familiaris | - |
4.2.1.3 | lens epithelium | - |
Canis lupus familiaris | - |
4.2.1.3 | retinal pigment epithelium | - |
Canis lupus familiaris | - |