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Literature summary extracted from

  • Bank, U.; Tadje, J.; Taeger, M.; Wolke, C.; Bukowska, A.; Ittenson, A.; Reinhold, D.; Helmuth, M.; Ansorge, S.; Shakespeare, A.; Vieth, M.; Malfertheiner, P.; Naumann, M.; Lendeckel, U.
    Inhibition of alanyl-aminopeptidase on CD4+CD25+ regulatory T-cells enhances expression of FoxP3 and TGF-beta1 and ameliorates acute colitis in mice (2007), Int. J. Mol. Med., 20, 483-492.
    View publication on PubMed

Application

EC Number Application Comment Organism
3.4.11.2 medicine pre-treatment of CD24+Cd25+ T-cells with aminopeptidase N inhibitor phebestin substantially enhances the suppressive activity of these cells and increases expression levels of transforming growth factor TGF-beta1 and FoxP3 and ameliorates acute colitis Mus musculus

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.4.11.2 phebestin
-
 Mus musculus
3.4.11.14 phebestin
-
 Mus musculus

Organism

EC Number Organism UniProt Comment Textmining
3.4.11.2 Mus musculus
-
-
-
3.4.11.14 Mus musculus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.4.11.2 splenocyte
-
 Mus musculus
-
3.4.11.2 T-cell CD24+Cd25+ T-cell Mus musculus
-
3.4.11.14 splenocyte
-
 Mus musculus
-
3.4.11.14 T-cell
-
 Mus musculus
-

Synonyms

EC Number Synonyms Comment Organism
3.4.11.14 alanyl-aminopeptidase
-
 Mus musculus