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Literature summary extracted from

  • Hrabchak, C.; Henderson, H.; Varmuza, S.
    A testis specific isoform of endophilin B1, endophilin B1t, interacts specifically with protein phosphatase-1c gamma2 in mouse testis and is abnormally expressed in PP1c gamma null mice (2007), Biochemistry, 46, 4635-4644.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
3.1.3.16 expressed in Saccharomyces cerevisiae strain AH109 Mus musculus

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.1.3.16 endophilin B1t
-
 Mus musculus
3.1.3.16 neurabin I
-
 Mus musculus

Organism

EC Number Organism UniProt Comment Textmining
3.1.3.16 Mus musculus
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
3.1.3.16 there is no reliable method of separating native PP1c isoforms directly from testis without contamination Mus musculus

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.1.3.16 testis
-
 Mus musculus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.1.3.16 phosphoprotein + H2O
-
 Mus musculus protein + phosphate
-
 ?

Synonyms

EC Number Synonyms Comment Organism
3.1.3.16 PP1cgamma
-
 Mus musculus
3.1.3.16 protein phosphatase-1c gamma2 isoform of protein phosphatase 1 Mus musculus
3.1.3.16 serine/threonine phosphatase
-
 Mus musculus

IC50 Value

EC Number IC50 Value IC50 Value Maximum Comment Organism Inhibitor Structure
3.1.3.16 0.000012
-
 at 37°C, in 50 mM Tris-HCl, pH 7.5, 1 mg/ml bovine serum albumin, 1 mM MnCl2, and 0.1% beta-mercaptoethanol Mus musculus neurabin I
3.1.3.16 0.0005
-
 at 37°C, in 50 mM Tris-HCl, pH 7.5, 1 mg/ml bovine serum albumin, 1 mM MnCl2, and 0.1% beta-mercaptoethanol Mus musculus endophilin B1t