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Literature summary extracted from

  • Pezza, J.A.; Stopa, J.D.; Brunyak, E.M.; Allen, K.N.; Tolan, D.R.
    Thermodynamic analysis shows conformational coupling and dynamics confer substrate specificity in fructose-1,6-bisphosphate aldolase (2007), Biochemistry, 46, 13010-13018.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

EC Number Cloned (Comment) Organism
4.1.2.13 expressed in Escherichia coli Oryctolagus cuniculus

Inhibitors

EC Number Inhibitors Comment Organism Structure
4.1.2.13 CuSO4 0.02 mM, inactivation Oryctolagus cuniculus
4.1.2.13 o-phenanthroline 0.06 mM, inactivation Oryctolagus cuniculus

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
4.1.2.13 0.0095
-
 D-fructose 1,6-bisphosphate at 30°C Oryctolagus cuniculus
4.1.2.13 40
-
 D-Fructose 1-phosphate at 30°C Oryctolagus cuniculus

Organism

EC Number Organism UniProt Comment Textmining
4.1.2.13 Oryctolagus cuniculus P00883
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
4.1.2.13 CM-Sepharose CL-6B chromatography Oryctolagus cuniculus

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4.1.2.13 D-fructose 1,6-bisphosphate
-
 Oryctolagus cuniculus glycerone phosphate + D-glyceraldehyde 3-phosphate
-
 ?
4.1.2.13 D-Fructose 1-phosphate
-
 Oryctolagus cuniculus Glycerone phosphate + D-glyceraldehyde
-
 ?

Synonyms

EC Number Synonyms Comment Organism
4.1.2.13 aldolase A
-
 Oryctolagus cuniculus

Turnover Number [1/s]

EC Number Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
4.1.2.13 0.63
-
 D-Fructose 1-phosphate at 30°C Oryctolagus cuniculus
4.1.2.13 10.2
-
 D-fructose 1,6-bisphosphate at 30°C Oryctolagus cuniculus