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Literature summary extracted from

  • Kleeb, A.C.; Kast, P.; Hilvert, D.
    A monofunctional and thermostable prephenate dehydratase from the archaeon Methanocaldococcus jannaschii (2006), Biochemistry, 45, 14101-14110.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
4.2.1.51 pheA gene is cloned and expressed in Escherichia coli Methanocaldococcus jannaschii

Inhibitors

EC Number Inhibitors Comment Organism Structure
4.2.1.51 L-Phe feedback-inhibition Methanocaldococcus jannaschii

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
4.2.1.51 0.022
-
 prephenate 30°C Methanocaldococcus jannaschii

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
4.2.1.51 31413
-
 x * 31413, ESI mass spectrometry Methanocaldococcus jannaschii
4.2.1.51 31415
-
 x * 31415, calculated from sequence Methanocaldococcus jannaschii
4.2.1.51 45600
-
 gel filtration Methanocaldococcus jannaschii

Organism

EC Number Organism UniProt Comment Textmining
4.2.1.51 Methanocaldococcus jannaschii
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
4.2.1.51
-
 Methanocaldococcus jannaschii

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4.2.1.51 prephenate
-
 Methanocaldococcus jannaschii phenylpyruvate + H2O + CO2
-
 ?

Subunits

EC Number Subunits Comment Organism
4.2.1.51 ? x * 31413, ESI mass spectrometry Methanocaldococcus jannaschii
4.2.1.51 ? x * 31415, calculated from sequence Methanocaldococcus jannaschii

Synonyms

EC Number Synonyms Comment Organism
4.2.1.51 MjPDT
-
 Methanocaldococcus jannaschii

Temperature Stability [°C]

EC Number Temperature Stability Minimum [°C] Temperature Stability Maximum [°C] Comment Organism
4.2.1.51 94
-
 MjPDT unfolds in a two-state manner, Tm: 94°C Methanocaldococcus jannaschii

Turnover Number [1/s]

EC Number Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
4.2.1.51 12.3
-
 prephenate 30°C Methanocaldococcus jannaschii

Ki Value [mM]

EC Number Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
4.2.1.51 0.0005
-
 L-Phe
-
 Methanocaldococcus jannaschii