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Literature summary extracted from

  • Hsieh, M.H.; Goodman, H.M.
    The Arabidopsis IspH homolog is involved in the plastid nonmevalonate pathway of isoprenoid biosynthesis (2005), Plant Physiol., 138, 641-653.
    View publication on PubMedView publication on EuropePMC

Activating Compound

EC Number Activating Compound Comment Organism Structure
1.1.1.267 additional information the enzyme is inducible by light Arabidopsis thaliana

Cloned(Commentary)

EC Number Cloned (Comment) Organism
1.1.1.267 gene ispC, expression analysis, light-dependent expression pattern, overview Arabidopsis thaliana

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.1.1.267 1-deoxy-D-xylulose 5-phosphate + NADPH + H+ Arabidopsis thaliana second committed step in isopentenyl diphosphate biosynthesis via the plastidial nonmevalonate pathway of isoprenoid biosynthesis, overview 2-C-methyl-D-erythritol 4-phosphate + NADP+
-
?
1.17.7.1 2-C-methyl-D-erythritol 2,4-cyclodiphosphate + 2 reduced ferredoxin Arabidopsis thaliana the enzyme is involved in the non-mevalonate pathway for isoprenoid biosynthesis (E)-4-hydroxy-3-methylbut-2-en-1-yl diphosphate + H2O + 2 oxidized ferredoxin
-
?

Organism

EC Number Organism UniProt Comment Textmining
1.1.1.267 Arabidopsis thaliana Q9XFS9 gene ispC
-
1.17.7.1 Arabidopsis thaliana F4K0E8
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.1.1.267 1-deoxy-D-xylulose 5-phosphate + NADPH + H+
-
Arabidopsis thaliana 2-C-methyl-D-erythritol 4-phosphate + NADP+
-
?
1.1.1.267 1-deoxy-D-xylulose 5-phosphate + NADPH + H+ second committed step in isopentenyl diphosphate biosynthesis via the plastidial nonmevalonate pathway of isoprenoid biosynthesis, overview Arabidopsis thaliana 2-C-methyl-D-erythritol 4-phosphate + NADP+
-
?
1.17.7.1 2-C-methyl-D-erythritol 2,4-cyclodiphosphate + 2 reduced ferredoxin
-
Arabidopsis thaliana (E)-4-hydroxy-3-methylbut-2-en-1-yl diphosphate + H2O + 2 oxidized ferredoxin
-
?
1.17.7.1 2-C-methyl-D-erythritol 2,4-cyclodiphosphate + 2 reduced ferredoxin the enzyme is involved in the non-mevalonate pathway for isoprenoid biosynthesis Arabidopsis thaliana (E)-4-hydroxy-3-methylbut-2-en-1-yl diphosphate + H2O + 2 oxidized ferredoxin
-
?

Synonyms

EC Number Synonyms Comment Organism
1.1.1.267 1-deoxy-D-xylulose 5-phosphate reductoisomerase
-
Arabidopsis thaliana
1.1.1.267 DOXP reductoisomerase
-
Arabidopsis thaliana
1.1.1.267 DXR
-
Arabidopsis thaliana
1.1.1.267 IspC
-
Arabidopsis thaliana
1.17.7.1 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase
-
Arabidopsis thaliana
1.17.7.1 IspG ambiguous Arabidopsis thaliana

Cofactor

EC Number Cofactor Comment Organism Structure
1.1.1.267 NADPH
-
Arabidopsis thaliana

Expression

EC Number Organism Comment Expression
1.17.7.1 Arabidopsis thaliana expression is induced by light up

General Information

EC Number General Information Comment Organism
1.17.7.1 metabolism the enzyme is involved in the non-mevalonate pathway for isoprenoid biosynthesis Arabidopsis thaliana