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Literature summary extracted from

  • Lee, S.Y.; Lee, C.O.
    Inhibition of Na+-K+ pump and L-type Ca2+ channel by glibenclamide in guinea pig ventricular myocytes (2005), J. Pharmacol. Exp. Ther., 312, 61-68.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
7.2.2.13 glibenclamide
-
 Cavia porcellus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
7.2.2.13 membrane
-
 Cavia porcellus 16020
-

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
7.2.2.13 ADP + phosphate + Na+/out Cavia porcellus
-
 ATP + H2O + Na+/in
-
 ?
7.2.2.13 ATP + H2O + K+/in Cavia porcellus
-
 ADP + phosphate + K+/out
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
7.2.2.13 Cavia porcellus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
7.2.2.13 myocyte ventricular myocyte Cavia porcellus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
7.2.2.13 ADP + phosphate + Na+/out
-
 Cavia porcellus ATP + H2O + Na+/in
-
 ?
7.2.2.13 ATP + H2O + K+/in
-
 Cavia porcellus ADP + phosphate + K+/out
-
 ?

Synonyms

EC Number Synonyms Comment Organism
7.2.2.13 Na+-K+ pump
-
 Cavia porcellus

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
7.2.2.13 37
-
 myocytes in the experimental chamber for measurement of Na+-K+ pump current Cavia porcellus

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
7.2.2.13 7.4
-
 myocytes in the experimental chamber for measurement of Na+-K+ pump current Cavia porcellus