EC Number | Crystallization (Comment) | Organism |
---|---|---|
1.3.1.48 | leukotriene B4 12-hydroxydehydrogenase/15-oxo-prostaglandin 13-reductase complex in ternary complex with indomethacin and NADP+. Indomethacin binds in anti-configuration at one of the active side clefts of the homodimer interface of the enzyme. The chlorobenzene is buried in the hydrophobic pore and the carboxyl group interacts with the guanidino group of R56 and the phenolic hydroxyl group of Y262 | Cavia porcellus |
EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
1.3.1.48 | indomethacin | - |
Cavia porcellus |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
1.3.1.48 | Cavia porcellus | - |
- |
- |