EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
2.5.1.22 | 1-aminooxy-3-N-(3-aminopropyl)-aminopropane | competitive inhibitor | Mus musculus | |
2.5.1.22 | 3-(RS)-(5'-deoxy-5'-carbaadenos-6'-yl)spermidine | IC50: 750 nM | Mus musculus | |
2.5.1.22 | N-(3-aminopropyl)cyclohexylamine | IC50: 0.2 mM | Mus musculus | |
2.5.1.22 | N-butyl-1,3-diaminopropane | IC50: 0.4 mM | Mus musculus | |
2.5.1.22 | N-[(2-aminooxyethyl)-1,4-diaminobutane] | competitive inhibitor | Mus musculus | |
2.5.1.22 | S-adenosyl-1,12-diamino-3-thio-9-azadodecane | IC50: 20 nM | Mus musculus |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
2.5.1.22 | Mus musculus | - |
- |
- |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.5.1.22 | S-adenosyl-L-methioninamine + spermidine | - |
Mus musculus | 5'-methylthioadenosine + spermine | - |
? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
2.5.1.22 | SpmS | - |
Mus musculus |
EC Number | Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|---|
2.5.1.22 | 0.0015 | - |
1-aminooxy-3-N-(3-aminopropyl)-aminopropane | - |
Mus musculus | |
2.5.1.22 | 0.186 | - |
N-[(2-aminooxyethyl)-1,4-diaminobutane] | - |
Mus musculus |
EC Number | IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|---|
2.5.1.22 | 0.00002 | - |
IC50: 20 nM | Mus musculus | S-adenosyl-1,12-diamino-3-thio-9-azadodecane | |
2.5.1.22 | 0.00075 | - |
IC50: 750 nM | Mus musculus | 3-(RS)-(5'-deoxy-5'-carbaadenos-6'-yl)spermidine | |
2.5.1.22 | 0.2 | - |
IC50: 0.2 mM | Mus musculus | N-(3-aminopropyl)cyclohexylamine | |
2.5.1.22 | 0.4 | - |
IC50: 0.4 mM | Mus musculus | N-butyl-1,3-diaminopropane |