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Literature summary extracted from

  • Wolucka, B.A.; Communi, D.
    Mycobacterium tuberculosis possesses a functional enzyme for the synthesis of vitamin C, L-gulono-1,4-lactone dehydrogenase (2006), FEBS J., 273, 4435-4445.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.1.3.8 Cu2+
-
 Mycobacterium tuberculosis
1.1.3.8 N-ethylmaleimide
-
 Mycobacterium tuberculosis
1.1.3.8 Zn2+
-
 Mycobacterium tuberculosis

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
1.1.3.8 5.5
-
 L-gulono-1,4-lactone the FAD-binding motif Rv1771 protein is a metalloenzyme that oxidizes L-gulono-1,4-lactone Mycobacterium tuberculosis

Organism

EC Number Organism UniProt Comment Textmining
1.1.3.8 Mycobacterium tuberculosis
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.1.3.8 L-glucono-1,4-lactone + O2
-
 Mycobacterium tuberculosis L-xylo-hex-3-ulonolactone + H2O2
-
 r
1.1.3.8 L-gulono-1,4-lactone + O2
-
 Mycobacterium tuberculosis L-xylo-hex-2-ulono-1,4-lactone + H2O2
-
 r

Synonyms

EC Number Synonyms Comment Organism
1.1.3.8 GLO
-
 Mycobacterium tuberculosis
1.1.3.8 L-gulono-1,4-lactone dehydrogenase
-
 Mycobacterium tuberculosis

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
1.1.3.8 7.5 8
-
 Mycobacterium tuberculosis