Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Khan, M.T.H.; Choudhary, I.; Rahman, A.U.; Mamedova, R.P.; Agzamova, M.A.; Sultankhodzhaev, M.N.; Isaev, M.I.
    Tyrosinase inhibition studies of cycloartane and cucurbitane glycosides and their structureactivity relationships (2006), Bioorg. Med. Chem., 14, 6085-6088.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.10.3.1 askendoside B IC50 : 0.014 mM Agaricus bisporus
1.10.3.1 askendoside D
-
 Agaricus bisporus
1.10.3.1 bryoamaride
-
 Agaricus bisporus
1.10.3.1 cucurbitane glycosides isolated from Bryonia, structure–activity relationships, overview Agaricus bisporus
1.10.3.1 cycloartane glycosides isolated from Astragalus sp., structure–activity relationships, overview Agaricus bisporus
1.10.3.1 cyclocarposide
-
 Agaricus bisporus
1.10.3.1 cycloorbicoside G
-
 Agaricus bisporus
1.10.3.1 cyclosieversioside F
-
 Agaricus bisporus
1.10.3.1 kojic acid
-
 Agaricus bisporus
1.10.3.1 L-mimosine
-
 Agaricus bisporus
1.10.3.1 additional information no inhibition by cycloalpioside D, cycloorbicoside A, askendoside G, and cucurbitacin L Agaricus bisporus

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
1.10.3.1 Cu2+
-
 Agaricus bisporus

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.10.3.1 L-dopa + 1/2 O2 Agaricus bisporus
-
 L-dopaquinone + H2O
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
1.10.3.1 Agaricus bisporus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.10.3.1 commercial preparation
-
 Agaricus bisporus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.10.3.1 L-dopa + 1/2 O2
-
 Agaricus bisporus L-dopaquinone + H2O
-
 ?
1.10.3.1 additional information multifunctional enzyme Agaricus bisporus ?
-
 ?

Synonyms

EC Number Synonyms Comment Organism
1.10.3.1 More cf. 1.14.18.1 Agaricus bisporus
1.10.3.1 tyrosinase
-
 Agaricus bisporus

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
1.10.3.1 25
-
 assay at Agaricus bisporus

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
1.10.3.1 6.8
-
 assay at Agaricus bisporus

IC50 Value

EC Number IC50 Value IC50 Value Maximum Comment Organism Inhibitor Structure
1.10.3.1 0.014
-
 IC50 : 0.014 mM Agaricus bisporus askendoside B