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Literature summary extracted from

  • Vinogradov, A.D.; Grivennikova, V.G.
    Generation of superoxide-radical by the NADH:ubiquinone oxidoreductase of heart mitochondria (2005), Biochemistry (Moscow), 70, 120-127.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
7.1.1.2 NAD+ weak inhibitor Bos taurus
7.1.1.2 rotenone 0.01 mM, complete inhibition Bos taurus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
7.1.1.2 mitochondrion
-
 Bos taurus 5739
-

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
7.1.1.2 Fe-S
-
 Bos taurus

Organism

EC Number Organism UniProt Comment Textmining
7.1.1.2 Bos taurus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
7.1.1.2 heart
-
 Bos taurus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
7.1.1.2 2 ferricytochrome c + NADH
-
 Bos taurus 2 ferrocytochrome c + NAD+ + H+
-
 ?
7.1.1.2 NADH + ubiquinone
-
 Bos taurus NAD+ + ubiquinol
-
 ?

Synonyms

EC Number Synonyms Comment Organism
7.1.1.2 complex I
-
 Bos taurus
7.1.1.2 NADH:ubiquinone oxidoreductase
-
 Bos taurus

Cofactor

EC Number Cofactor Comment Organism Structure
7.1.1.2 FMN
-
 Bos taurus
7.1.1.2 NADH
-
 Bos taurus