Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Traver, S.; Splingard, A.; Gaudriault, G.; De Gunzburg, J.
    The RGS (regulator of G-protein signalling) and GoLoco domains of RGS14 co-operate to regulate Gi-mediated signalling (2004), Biochem. J., 379, 627-632.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
3.6.5.1 RGS14 protein
-
 Mammalia

Protein Variants

EC Number Protein Variants Comment Organism
3.6.5.1 E92A/N93A RGS14 mutant Mammalia
3.6.5.1 E92A/N93A/R519F RGS14 mutant Mammalia
3.6.5.1 GoLoco RGS14 mutant Mammalia
3.6.5.1 Myr-Pal-GoLoco RGS14 mutant Mammalia
3.6.5.1 Myr-Pal-GoLoco R519F RGS14 mutant Mammalia
3.6.5.1 R336L RGS14 mutant Mammalia
3.6.5.1 R519F RGS14 mutant Mammalia
3.6.5.1 RGS RGS14 mutant Mammalia
3.6.5.1 RID-GoLoco RGS14 mutant Mammalia
3.6.5.1 RID-GoLoco R336L RGS14 mutant Mammalia
3.6.5.1 RID-GoLoco R519F RGS14 mutant Mammalia

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.6.5.1 GTP + H2O Mammalia
-
 GDP + phosphate
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
3.6.5.1 Mammalia
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.6.5.1 GTP + H2O
-
 Mammalia GDP + phosphate
-
 ?

Subunits

EC Number Subunits Comment Organism
3.6.5.1 heterotrimer Galpha subunit, GDP-bound inactive, GTP-bound active and betagamma dimer Mammalia

Synonyms

EC Number Synonyms Comment Organism
3.6.5.1 GTP phosphohydrolase
-
 Mammalia
3.6.5.1 heterotrimeric G-protein GTPase
-
 Mammalia