BRENDA - Enzyme Database show

Monoterpene metabolism. Cloning, expression, and characterization of (-)-isopiperitenol/(-)-carveol dehydrogenase of peppermint and spearmint

Ringer, K.L.; Davis, E.M.; Croteau, R.; Plant Physiol. 137, 863-872 (2005)

Data extracted from this reference:

Cloned(Commentary)
EC Number
Commentary
Organism
1.1.1.223
expressed in Escherichia coli
Mentha x piperita
1.1.1.243
expressed in Escherichia coli
Mentha spicata
Localization
EC Number
Localization
Commentary
Organism
GeneOntology No.
Textmining
1.3.1.82
soluble
-
Mentha x piperita
-
-
Natural Substrates/ Products (Substrates)
EC Number
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
1.3.1.81
2 (+)-pulegone + 2 NADPH + 2 H+
Mentha x piperita
pathways of monoterpene biosynthesis, overview
(-)-menthone + (+)-isomenthone + 2 NADP+
-
-
?
1.3.1.81
2 (+)-pulegone + 2 NADPH + 2 H+
Mentha spicata
pathways of monoterpene biosynthesis, overview
(-)-menthone + (+)-isomenthone + 2 NADP+
-
-
?
1.3.1.82
(-)-isopiperitenone + NADPH + H+
Mentha x piperita
the soluble NADPH-dependent, endocyclic double-bond reductase reduces (-)-isopiperitenone to (+)-cis-isopulegone, pathways of monoterpene biosynthesis, overview
(+)-cis-isopulegone + NADP+
-
-
?
1.3.1.82
(-)-isopiperitenone + NADPH + H+
Mentha spicata
the soluble NADPH-dependent, endocyclic double-bond reductase reduces (-)-isopiperitenone to (+)-cis-isopulegone, pathways of monoterpene biosynthesis, overview
(+)-cis-isopulegone + NADP+
-
-
?
Organism
EC Number
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
1.1.1.223
Mentha x piperita
-
sterile cross between Mentha spicata and Mentha aquatica
-
1.1.1.243
Mentha spicata
-
-
-
1.3.1.81
Mentha spicata
-
-
-
1.3.1.81
Mentha x piperita
-
-
-
1.3.1.82
Mentha spicata
-
-
-
1.3.1.82
Mentha x piperita
-
-
-
Substrates and Products (Substrate)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
1.1.1.223
(-)-trans-isopiperitenol + NADP+
-
670589
Mentha x piperita
(-)-isopiperitenone + NADPH + H+
-
-
-
?
1.1.1.243
(-)-trans-isopiperitenol + NADP+
-
670589
Mentha spicata
(-)-isopiperitenone + NADPH + H+
-
-
-
?
1.3.1.81
2 (+)-pulegone + 2 NADPH + 2 H+
-
670589
Mentha spicata
(-)-menthone + (+)-isomenthone + 2 NADP+
-
-
-
?
1.3.1.81
2 (+)-pulegone + 2 NADPH + 2 H+
pathways of monoterpene biosynthesis, overview
670589
Mentha x piperita
(-)-menthone + (+)-isomenthone + 2 NADP+
-
-
-
?
1.3.1.81
2 (+)-pulegone + 2 NADPH + 2 H+
pathways of monoterpene biosynthesis, overview
670589
Mentha spicata
(-)-menthone + (+)-isomenthone + 2 NADP+
-
-
-
?
1.3.1.81
2 (+)-pulegone + 2 NADPH + 2 H+
the NADPH-dependent reductase reduces the conjugated double bond to yield both (-)-menthone and (+)-isomenthone
670589
Mentha x piperita
(-)-menthone + (+)-isomenthone + 2 NADP+
-
-
-
?
1.3.1.82
(-)-isopiperitenone + NADPH + H+
-
670589
Mentha x piperita
(+)-cis-isopulegone + NADP+
-
-
-
?
1.3.1.82
(-)-isopiperitenone + NADPH + H+
-
670589
Mentha spicata
(+)-cis-isopulegone + NADP+
-
-
-
?
1.3.1.82
(-)-isopiperitenone + NADPH + H+
the soluble NADPH-dependent, endocyclic double-bond reductase reduces (-)-isopiperitenone to (+)-cis-isopulegone, pathways of monoterpene biosynthesis, overview
670589
Mentha x piperita
(+)-cis-isopulegone + NADP+
-
-
-
?
1.3.1.82
(-)-isopiperitenone + NADPH + H+
the soluble NADPH-dependent, endocyclic double-bond reductase reduces (-)-isopiperitenone to (+)-cis-isopulegone, pathways of monoterpene biosynthesis, overview
670589
Mentha spicata
(+)-cis-isopulegone + NADP+
-
-
-
?
Cofactor
EC Number
Cofactor
Commentary
Organism
Structure
1.1.1.223
NADP+
-
Mentha x piperita
1.1.1.243
NADP+
-
Mentha spicata
1.3.1.81
NADPH
-
Mentha spicata
1.3.1.81
NADPH
-
Mentha x piperita
1.3.1.82
NADPH
-
Mentha spicata
1.3.1.82
NADPH
dependent on
Mentha x piperita
Cloned(Commentary) (protein specific)
EC Number
Commentary
Organism
1.1.1.223
expressed in Escherichia coli
Mentha x piperita
1.1.1.243
expressed in Escherichia coli
Mentha spicata
Cofactor (protein specific)
EC Number
Cofactor
Commentary
Organism
Structure
1.1.1.223
NADP+
-
Mentha x piperita
1.1.1.243
NADP+
-
Mentha spicata
1.3.1.81
NADPH
-
Mentha spicata
1.3.1.81
NADPH
-
Mentha x piperita
1.3.1.82
NADPH
-
Mentha spicata
1.3.1.82
NADPH
dependent on
Mentha x piperita
Localization (protein specific)
EC Number
Localization
Commentary
Organism
GeneOntology No.
Textmining
1.3.1.82
soluble
-
Mentha x piperita
-
-
Natural Substrates/ Products (Substrates) (protein specific)
EC Number
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
1.3.1.81
2 (+)-pulegone + 2 NADPH + 2 H+
Mentha x piperita
pathways of monoterpene biosynthesis, overview
(-)-menthone + (+)-isomenthone + 2 NADP+
-
-
?
1.3.1.81
2 (+)-pulegone + 2 NADPH + 2 H+
Mentha spicata
pathways of monoterpene biosynthesis, overview
(-)-menthone + (+)-isomenthone + 2 NADP+
-
-
?
1.3.1.82
(-)-isopiperitenone + NADPH + H+
Mentha x piperita
the soluble NADPH-dependent, endocyclic double-bond reductase reduces (-)-isopiperitenone to (+)-cis-isopulegone, pathways of monoterpene biosynthesis, overview
(+)-cis-isopulegone + NADP+
-
-
?
1.3.1.82
(-)-isopiperitenone + NADPH + H+
Mentha spicata
the soluble NADPH-dependent, endocyclic double-bond reductase reduces (-)-isopiperitenone to (+)-cis-isopulegone, pathways of monoterpene biosynthesis, overview
(+)-cis-isopulegone + NADP+
-
-
?
Substrates and Products (Substrate) (protein specific)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
1.1.1.223
(-)-trans-isopiperitenol + NADP+
-
670589
Mentha x piperita
(-)-isopiperitenone + NADPH + H+
-
-
-
?
1.1.1.243
(-)-trans-isopiperitenol + NADP+
-
670589
Mentha spicata
(-)-isopiperitenone + NADPH + H+
-
-
-
?
1.3.1.81
2 (+)-pulegone + 2 NADPH + 2 H+
-
670589
Mentha spicata
(-)-menthone + (+)-isomenthone + 2 NADP+
-
-
-
?
1.3.1.81
2 (+)-pulegone + 2 NADPH + 2 H+
pathways of monoterpene biosynthesis, overview
670589
Mentha x piperita
(-)-menthone + (+)-isomenthone + 2 NADP+
-
-
-
?
1.3.1.81
2 (+)-pulegone + 2 NADPH + 2 H+
pathways of monoterpene biosynthesis, overview
670589
Mentha spicata
(-)-menthone + (+)-isomenthone + 2 NADP+
-
-
-
?
1.3.1.81
2 (+)-pulegone + 2 NADPH + 2 H+
the NADPH-dependent reductase reduces the conjugated double bond to yield both (-)-menthone and (+)-isomenthone
670589
Mentha x piperita
(-)-menthone + (+)-isomenthone + 2 NADP+
-
-
-
?
1.3.1.82
(-)-isopiperitenone + NADPH + H+
-
670589
Mentha x piperita
(+)-cis-isopulegone + NADP+
-
-
-
?
1.3.1.82
(-)-isopiperitenone + NADPH + H+
-
670589
Mentha spicata
(+)-cis-isopulegone + NADP+
-
-
-
?
1.3.1.82
(-)-isopiperitenone + NADPH + H+
the soluble NADPH-dependent, endocyclic double-bond reductase reduces (-)-isopiperitenone to (+)-cis-isopulegone, pathways of monoterpene biosynthesis, overview
670589
Mentha x piperita
(+)-cis-isopulegone + NADP+
-
-
-
?
1.3.1.82
(-)-isopiperitenone + NADPH + H+
the soluble NADPH-dependent, endocyclic double-bond reductase reduces (-)-isopiperitenone to (+)-cis-isopulegone, pathways of monoterpene biosynthesis, overview
670589
Mentha spicata
(+)-cis-isopulegone + NADP+
-
-
-
?