Literature summary extracted from

Jang, H.H.; Chi, Y.H.; Park, S.K.; Lee, S.S.; Lee, J.R.; Park, J.H.; Moon, J.C.; Lee, Y.M.; Kim, S.Y.; Lee, K.O.; Lee, S.Y.
Structural and functional regulation of eukaryotic 2-Cys peroxiredoxins including the plant ones in cellular defense-signaling mechanisms against oxidative stress (2006), Physiol. Plant., 126, 549-559.

Metals/Ions

EC Number	Metals/Ions	Comment	Organism	Structure
1.8.98.2	Mg2+	-	Homo sapiens
1.8.98.2	Mg2+	-	Saccharomyces cerevisiae

Organism

EC Number	Organism	UniProt	Comment	Textmining
1.8.98.2	Homo sapiens	-	-	-
1.8.98.2	Saccharomyces cerevisiae	-	-	-

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
1.8.98.2	peroxiredoxin-(S-hydroxy-S-oxocysteine) + ATP + 2 R-SH	-	Homo sapiens	peroxiredoxin-(S-hydroxycysteine) + ADP + phosphate + R-S-S-R	-	r
1.8.98.2	peroxiredoxin-(S-hydroxy-S-oxocysteine) + ATP + 2 R-SH	-	Saccharomyces cerevisiae	peroxiredoxin-(S-hydroxycysteine) + ADP + phosphate + R-S-S-R	-	r

Synonyms

EC Number	Synonyms	Comment	Organism
1.8.98.2	Srx1	-	Homo sapiens
1.8.98.2	Srx1	-	Saccharomyces cerevisiae

Cofactor

EC Number	Cofactor	Comment	Organism	Structure
1.8.98.2	ATP	-	Homo sapiens
1.8.98.2	ATP	-	Saccharomyces cerevisiae

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Release 2023.1 (January 2023)