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Literature summary extracted from

  • Galperin, M.Y.; Moroz, O.V.; Wilson, K.S.; Murzin, A.G.
    House cleaning, a part of good housekeeping (2006), Mol. Microbiol., 59, 5-19.
    View publication on PubMed

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.6.1.23 dUTP + H2O Staphylococcus aureus
-
 dUMP + diphosphate
-
 ?
3.6.1.23 dUTP + H2O Escherichia coli
-
 dUMP + diphosphate
-
 ?
3.6.1.23 dUTP + H2O Saccharomyces cerevisiae
-
 dUMP + diphosphate
-
 ?
3.6.1.23 dUTP + H2O Trypanosoma cruzi
-
 dUMP + diphosphate
-
 ?
3.6.1.23 dUTP + H2O Leishmania major
-
 dUMP + diphosphate
-
 ?
3.6.1.23 dUTP + H2O Campylobacter jejuni
-
 dUMP + diphosphate
-
 ?
3.6.1.23 dUTP + H2O Mycobacterium tuberculosis
-
 dUMP + diphosphate
-
 ?
3.6.1.23 dUTP + H2O Mycobacterium tuberculosis H37Rv
-
 dUMP + diphosphate
-
 ?
3.6.1.23 additional information Staphylococcus aureus biological functions in housekeeping, overview ?
-
 ?
3.6.1.23 additional information Escherichia coli biological functions in housekeeping, overview ?
-
 ?
3.6.1.23 additional information Saccharomyces cerevisiae biological functions in housekeeping, overview ?
-
 ?
3.6.1.23 additional information Trypanosoma cruzi biological functions in housekeeping, overview ?
-
 ?
3.6.1.23 additional information Leishmania major biological functions in housekeeping, overview ?
-
 ?
3.6.1.23 additional information Campylobacter jejuni biological functions in housekeeping, overview ?
-
 ?
3.6.1.23 additional information Mycobacterium tuberculosis biological functions in housekeeping, overview ?
-
 ?
3.6.1.23 additional information Mycobacterium tuberculosis H37Rv biological functions in housekeeping, overview ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
3.6.1.23 Campylobacter jejuni
-
-
-
3.6.1.23 Escherichia coli
-
-
-
3.6.1.23 Leishmania major
-
-
-
3.6.1.23 Mycobacterium tuberculosis P9WNS5
-
-
3.6.1.23 Mycobacterium tuberculosis H37Rv P9WNS5
-
-
3.6.1.23 Saccharomyces cerevisiae
-
-
-
3.6.1.23 Staphylococcus aureus
-
-
-
3.6.1.23 Trypanosoma cruzi
-
-
-

Reaction

EC Number Reaction Comment Organism Reaction ID
3.6.1.23 dUTP + H2O = dUMP + diphosphate structural organization and substrate binding modes Staphylococcus aureus
a
3.6.1.23 dUTP + H2O = dUMP + diphosphate structural organization and substrate binding modes Escherichia coli
a
3.6.1.23 dUTP + H2O = dUMP + diphosphate structural organization and substrate binding modes Saccharomyces cerevisiae
a
3.6.1.23 dUTP + H2O = dUMP + diphosphate structural organization and substrate binding modes Trypanosoma cruzi
a
3.6.1.23 dUTP + H2O = dUMP + diphosphate structural organization and substrate binding modes Leishmania major
a
3.6.1.23 dUTP + H2O = dUMP + diphosphate structural organization and substrate binding modes Campylobacter jejuni
a
3.6.1.23 dUTP + H2O = dUMP + diphosphate structural organization and substrate binding modes Mycobacterium tuberculosis
a

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.6.1.23 dUTP + H2O
-
 Staphylococcus aureus dUMP + diphosphate
-
 ?
3.6.1.23 dUTP + H2O
-
 Escherichia coli dUMP + diphosphate
-
 ?
3.6.1.23 dUTP + H2O
-
 Saccharomyces cerevisiae dUMP + diphosphate
-
 ?
3.6.1.23 dUTP + H2O
-
 Trypanosoma cruzi dUMP + diphosphate
-
 ?
3.6.1.23 dUTP + H2O
-
 Leishmania major dUMP + diphosphate
-
 ?
3.6.1.23 dUTP + H2O
-
 Campylobacter jejuni dUMP + diphosphate
-
 ?
3.6.1.23 dUTP + H2O
-
 Mycobacterium tuberculosis dUMP + diphosphate
-
 ?
3.6.1.23 dUTP + H2O
-
 Mycobacterium tuberculosis H37Rv dUMP + diphosphate
-
 ?
3.6.1.23 additional information biological functions in housekeeping, overview Staphylococcus aureus ?
-
 ?
3.6.1.23 additional information biological functions in housekeeping, overview Escherichia coli ?
-
 ?
3.6.1.23 additional information biological functions in housekeeping, overview Saccharomyces cerevisiae ?
-
 ?
3.6.1.23 additional information biological functions in housekeeping, overview Trypanosoma cruzi ?
-
 ?
3.6.1.23 additional information biological functions in housekeeping, overview Leishmania major ?
-
 ?
3.6.1.23 additional information biological functions in housekeeping, overview Campylobacter jejuni ?
-
 ?
3.6.1.23 additional information biological functions in housekeeping, overview Mycobacterium tuberculosis ?
-
 ?
3.6.1.23 additional information substrate specificity, no hydrolysis of canonical NTPs, overview Staphylococcus aureus ?
-
 ?
3.6.1.23 additional information substrate specificity, no hydrolysis of canonical NTPs, overview Escherichia coli ?
-
 ?
3.6.1.23 additional information substrate specificity, no hydrolysis of canonical NTPs, overview Saccharomyces cerevisiae ?
-
 ?
3.6.1.23 additional information substrate specificity, no hydrolysis of canonical NTPs, overview Trypanosoma cruzi ?
-
 ?
3.6.1.23 additional information substrate specificity, no hydrolysis of canonical NTPs, overview Leishmania major ?
-
 ?
3.6.1.23 additional information substrate specificity, no hydrolysis of canonical NTPs, overview Campylobacter jejuni ?
-
 ?
3.6.1.23 additional information substrate specificity, no hydrolysis of canonical NTPs, overview Mycobacterium tuberculosis ?
-
 ?
3.6.1.23 additional information biological functions in housekeeping, overview Mycobacterium tuberculosis H37Rv ?
-
 ?
3.6.1.23 additional information substrate specificity, no hydrolysis of canonical NTPs, overview Mycobacterium tuberculosis H37Rv ?
-
 ?

Subunits

EC Number Subunits Comment Organism
3.6.1.23 dimer homodimer Staphylococcus aureus
3.6.1.23 dimer homodimer Trypanosoma cruzi
3.6.1.23 dimer homodimer Leishmania major
3.6.1.23 dimer homodimer Campylobacter jejuni
3.6.1.23 trimer homotrimer Escherichia coli
3.6.1.23 trimer homotrimer Saccharomyces cerevisiae
3.6.1.23 trimer homotrimer Mycobacterium tuberculosis

Synonyms

EC Number Synonyms Comment Organism
3.6.1.23 dUTPase
-
 Staphylococcus aureus
3.6.1.23 dUTPase
-
 Escherichia coli
3.6.1.23 dUTPase
-
 Saccharomyces cerevisiae
3.6.1.23 dUTPase
-
 Trypanosoma cruzi
3.6.1.23 dUTPase
-
 Leishmania major
3.6.1.23 dUTPase
-
 Campylobacter jejuni
3.6.1.23 dUTPase
-
 Mycobacterium tuberculosis
3.6.1.23 More the enzyme belongs to the Nudix superfamily of enzymes Staphylococcus aureus
3.6.1.23 More the enzyme belongs to the Nudix superfamily of enzymes Escherichia coli
3.6.1.23 More the enzyme belongs to the Nudix superfamily of enzymes Saccharomyces cerevisiae
3.6.1.23 More the enzyme belongs to the Nudix superfamily of enzymes Trypanosoma cruzi
3.6.1.23 More the enzyme belongs to the Nudix superfamily of enzymes Leishmania major
3.6.1.23 More the enzyme belongs to the Nudix superfamily of enzymes Campylobacter jejuni
3.6.1.23 More the enzyme belongs to the Nudix superfamily of enzymes Mycobacterium tuberculosis