EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
1.1.1.149 | apigenin | high inhibition | Mus musculus | |
1.1.1.149 | fisetin | high inhibition | Mus musculus | |
1.1.1.149 | kaempferol | high inhibition | Mus musculus | |
1.1.1.149 | luteolin | high inhibition | Mus musculus | |
1.1.1.149 | naringenin | high inhibition | Mus musculus | |
1.1.1.149 | quercetin | high inhibition | Mus musculus |
EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|---|
1.1.1.149 | cytosol | - |
Mus musculus | 5829 | - |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
1.1.1.149 | 17alpha-hydroxyprogesterone + NAD(P)H | Mus musculus | NADPH is preferred to NADH in liver, while the kidney enzyme is specific for NADPH | 17alpha,20alpha-dihydroxypregn-4-en-3-one + NAD(P)+ | - |
r |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
1.1.1.149 | Mus musculus | - |
female and male mice | - |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
1.1.1.149 | kidney | - |
Mus musculus | - |
1.1.1.149 | liver | - |
Mus musculus | - |
1.1.1.149 | lung | - |
Mus musculus | - |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
1.1.1.149 | 17alpha-hydroxyprogesterone + NAD(P)H | - |
Mus musculus | 17alpha,20alpha-dihydroxypregn-4-en-3-one + NAD(P)+ | - |
r | |
1.1.1.149 | 17alpha-hydroxyprogesterone + NAD(P)H | NADPH is preferred to NADH in liver, while the kidney enzyme is specific for NADPH | Mus musculus | 17alpha,20alpha-dihydroxypregn-4-en-3-one + NAD(P)+ | - |
r |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
1.1.1.149 | 20alpha-HSD | - |
Mus musculus |
EC Number | Cofactor | Comment | Organism | Structure |
---|---|---|---|---|
1.1.1.149 | NAD(P)+ | - |
Mus musculus | |
1.1.1.149 | NAD(P)H | NADPH is preferred to NADH in liver, while the kidney enzyme is specific for NADPH | Mus musculus |