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Literature summary extracted from

  • Gilbert, A.M.; Failli, A.; Shumsky, J.; Yang, Y.; Severin, A.; Singh, G.; Hu, W.; Keeney, D.; Petersen, P.J.; Katz, A.H.
    Pyrazolidine-3,5-diones and 5-hydroxy-1H-pyrazol-3(2H)-ones, inhibitors of UDP-N-acetylenolpyruvyl glucosamine reductase (2006), J. Med. Chem., 49, 6027-6036.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
1.3.1.98 overexpression in strain BL21(DE3) Escherichia coli

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.3.1.98 1,2-bis(3,4-dichlorophenyl)-5-hydroxy-3-oxo-2,3-dihydro-1H-pyrazole-4-carboxylic acid (3,4-dichlorophenyl)amide
-
 Candida albicans
1.3.1.98 1,2-bis(3,4-dichlorophenyl)-5-hydroxy-3-oxo-2,3-dihydro-1H-pyrazole-4-carboxylic acid (3,4-dichlorophenyl)amide
-
 Enterococcus faecalis
1.3.1.98 1,2-bis(3,4-dichlorophenyl)-5-hydroxy-3-oxo-2,3-dihydro-1H-pyrazole-4-carboxylic acid (3,4-dichlorophenyl)amide
-
 Escherichia coli
1.3.1.98 1,2-bis(3,4-dichlorophenyl)-5-hydroxy-3-oxo-2,3-dihydro-1H-pyrazole-4-carboxylic acid (3,4-dichlorophenyl)amide
-
 Staphylococcus aureus
1.3.1.98 1,2-bis(3,4-dichlorophenyl)-5-hydroxy-3-oxo-2,3-dihydro-1H-pyrazole-4-carboxylic acid (3,4-dichlorophenyl)amide
-
 Streptococcus pneumoniae
1.3.1.98 1,2-bis(3,4-dichlorophenyl)-5-hydroxy-3-oxo-2,3-dihydro-1H-pyrazole-4-carboxylic acid 4-tolylamide
-
 Candida albicans
1.3.1.98 1,2-bis(3,4-dichlorophenyl)-5-hydroxy-3-oxo-2,3-dihydro-1H-pyrazole-4-carboxylic acid 4-tolylamide
-
 Enterococcus faecalis
1.3.1.98 1,2-bis(3,4-dichlorophenyl)-5-hydroxy-3-oxo-2,3-dihydro-1H-pyrazole-4-carboxylic acid 4-tolylamide
-
 Escherichia coli
1.3.1.98 1,2-bis(3,4-dichlorophenyl)-5-hydroxy-3-oxo-2,3-dihydro-1H-pyrazole-4-carboxylic acid 4-tolylamide
-
 Staphylococcus aureus
1.3.1.98 1,2-bis(3,4-dichlorophenyl)-5-hydroxy-3-oxo-2,3-dihydro-1H-pyrazole-4-carboxylic acid 4-tolylamide
-
 Streptococcus pneumoniae
1.3.1.98 1,2-bis(3,4-dichlorophenyl)pyrazolidine-3,5-dione
-
 Candida albicans
1.3.1.98 1,2-bis(3,4-dichlorophenyl)pyrazolidine-3,5-dione
-
 Enterococcus faecalis
1.3.1.98 1,2-bis(3,4-dichlorophenyl)pyrazolidine-3,5-dione
-
 Escherichia coli
1.3.1.98 1,2-bis(3,4-dichlorophenyl)pyrazolidine-3,5-dione
-
 Staphylococcus aureus
1.3.1.98 1,2-bis(3,4-dichlorophenyl)pyrazolidine-3,5-dione
-
 Streptococcus pneumoniae
1.3.1.98 1,2-bis(3-chlorophenyl)-3,5-dioxopyrazolidine-4-carboxylic acid (4-chlorophenyl)amide
-
 Candida albicans
1.3.1.98 1,2-bis(3-chlorophenyl)-3,5-dioxopyrazolidine-4-carboxylic acid (4-chlorophenyl)amide
-
 Enterococcus faecalis
1.3.1.98 1,2-bis(3-chlorophenyl)-3,5-dioxopyrazolidine-4-carboxylic acid (4-chlorophenyl)amide
-
 Escherichia coli
1.3.1.98 1,2-bis(3-chlorophenyl)-3,5-dioxopyrazolidine-4-carboxylic acid (4-chlorophenyl)amide
-
 Staphylococcus aureus
1.3.1.98 1,2-bis(3-chlorophenyl)-3,5-dioxopyrazolidine-4-carboxylic acid (4-chlorophenyl)amide
-
 Streptococcus pneumoniae
1.3.1.98 1,2-bis(3-chlorophenyl)-5-hydroxy-3-oxo-2,3-dihydro-1H-pyrazole-4-carboxylic acid (4-trifluoromethylphenyl)amide
-
 Candida albicans
1.3.1.98 1,2-bis(3-chlorophenyl)-5-hydroxy-3-oxo-2,3-dihydro-1H-pyrazole-4-carboxylic acid (4-trifluoromethylphenyl)amide
-
 Enterococcus faecalis
1.3.1.98 1,2-bis(3-chlorophenyl)-5-hydroxy-3-oxo-2,3-dihydro-1H-pyrazole-4-carboxylic acid (4-trifluoromethylphenyl)amide
-
 Escherichia coli
1.3.1.98 1,2-bis(3-chlorophenyl)-5-hydroxy-3-oxo-2,3-dihydro-1H-pyrazole-4-carboxylic acid (4-trifluoromethylphenyl)amide
-
 Staphylococcus aureus
1.3.1.98 1,2-bis(3-chlorophenyl)-5-hydroxy-3-oxo-2,3-dihydro-1H-pyrazole-4-carboxylic acid (4-trifluoromethylphenyl)amide
-
 Streptococcus pneumoniae
1.3.1.98 1,2-bis(3-chlorophenyl)pyrazolidine-3,5-dione
-
 Candida albicans
1.3.1.98 1,2-bis(3-chlorophenyl)pyrazolidine-3,5-dione
-
 Enterococcus faecalis
1.3.1.98 1,2-bis(3-chlorophenyl)pyrazolidine-3,5-dione
-
 Escherichia coli
1.3.1.98 1,2-bis(3-chlorophenyl)pyrazolidine-3,5-dione
-
 Staphylococcus aureus
1.3.1.98 1,2-bis(3-chlorophenyl)pyrazolidine-3,5-dione
-
 Streptococcus pneumoniae
1.3.1.98 1,2-bis(4-chlorophenyl)-3,5-dioxo-N-phenylpyrazolidine-4-carboxamide
-
 Candida albicans
1.3.1.98 1,2-bis(4-chlorophenyl)-3,5-dioxo-N-phenylpyrazolidine-4-carboxamide
-
 Enterococcus faecalis
1.3.1.98 1,2-bis(4-chlorophenyl)-3,5-dioxo-N-phenylpyrazolidine-4-carboxamide
-
 Escherichia coli
1.3.1.98 1,2-bis(4-chlorophenyl)-3,5-dioxo-N-phenylpyrazolidine-4-carboxamide
-
 Staphylococcus aureus
1.3.1.98 1,2-bis(4-chlorophenyl)-3,5-dioxo-N-phenylpyrazolidine-4-carboxamide
-
 Streptococcus pneumoniae
1.3.1.98 1,2-bis(4-chlorophenyl)-4-(3,4-dichlorobenzoyl)-5-hydroxy-1,2-dihydropyrazol-3-one
-
 Candida albicans
1.3.1.98 1,2-bis(4-chlorophenyl)-4-(3,4-dichlorobenzoyl)-5-hydroxy-1,2-dihydropyrazol-3-one
-
 Enterococcus faecalis
1.3.1.98 1,2-bis(4-chlorophenyl)-4-(3,4-dichlorobenzoyl)-5-hydroxy-1,2-dihydropyrazol-3-one
-
 Escherichia coli
1.3.1.98 1,2-bis(4-chlorophenyl)-4-(3,4-dichlorobenzoyl)-5-hydroxy-1,2-dihydropyrazol-3-one
-
 Staphylococcus aureus
1.3.1.98 1,2-bis(4-chlorophenyl)-4-(3,4-dichlorobenzoyl)-5-hydroxy-1,2-dihydropyrazol-3-one
-
 Streptococcus pneumoniae
1.3.1.98 1,2-bis(4-chlorophenyl)-4-cyclohexanecarbonyl-5-hydroxy-1,2-dihydropyrazol-3-one
-
 Candida albicans
1.3.1.98 1,2-bis(4-chlorophenyl)-4-cyclohexanecarbonyl-5-hydroxy-1,2-dihydropyrazol-3-one
-
 Enterococcus faecalis
1.3.1.98 1,2-bis(4-chlorophenyl)-4-cyclohexanecarbonyl-5-hydroxy-1,2-dihydropyrazol-3-one
-
 Escherichia coli
1.3.1.98 1,2-bis(4-chlorophenyl)-4-cyclohexanecarbonyl-5-hydroxy-1,2-dihydropyrazol-3-one
-
 Staphylococcus aureus
1.3.1.98 1,2-bis(4-chlorophenyl)-4-cyclohexanecarbonyl-5-hydroxy-1,2-dihydropyrazol-3-one
-
 Streptococcus pneumoniae
1.3.1.98 1,2-bis(4-chlorophenyl)-5-hydroxy-3-oxo-2,3-dihydro-1H-pyrazole-4-carboxylic acid (1-naphthalen-2-ylethyl)amide
-
 Candida albicans
1.3.1.98 1,2-bis(4-chlorophenyl)-5-hydroxy-3-oxo-2,3-dihydro-1H-pyrazole-4-carboxylic acid (1-naphthalen-2-ylethyl)amide
-
 Enterococcus faecalis
1.3.1.98 1,2-bis(4-chlorophenyl)-5-hydroxy-3-oxo-2,3-dihydro-1H-pyrazole-4-carboxylic acid (1-naphthalen-2-ylethyl)amide
-
 Escherichia coli
1.3.1.98 1,2-bis(4-chlorophenyl)-5-hydroxy-3-oxo-2,3-dihydro-1H-pyrazole-4-carboxylic acid (1-naphthalen-2-ylethyl)amide
-
 Staphylococcus aureus
1.3.1.98 1,2-bis(4-chlorophenyl)-5-hydroxy-3-oxo-2,3-dihydro-1H-pyrazole-4-carboxylic acid (1-naphthalen-2-ylethyl)amide
-
 Streptococcus pneumoniae
1.3.1.98 1,2-bis(4-chlorophenyl)-5-hydroxy-3-oxo-2,3-dihydro-1H-pyrazole-4-carboxylic acid (2-chlorophenyl)amide
-
 Candida albicans
1.3.1.98 1,2-bis(4-chlorophenyl)-5-hydroxy-3-oxo-2,3-dihydro-1H-pyrazole-4-carboxylic acid (2-chlorophenyl)amide
-
 Enterococcus faecalis
1.3.1.98 1,2-bis(4-chlorophenyl)-5-hydroxy-3-oxo-2,3-dihydro-1H-pyrazole-4-carboxylic acid (2-chlorophenyl)amide
-
 Escherichia coli
1.3.1.98 1,2-bis(4-chlorophenyl)-5-hydroxy-3-oxo-2,3-dihydro-1H-pyrazole-4-carboxylic acid (2-chlorophenyl)amide
-
 Staphylococcus aureus
1.3.1.98 1,2-bis(4-chlorophenyl)-5-hydroxy-3-oxo-2,3-dihydro-1H-pyrazole-4-carboxylic acid (2-chlorophenyl)amide
-
 Streptococcus pneumoniae
1.3.1.98 1,2-bis(4-chlorophenyl)-5-hydroxy-3-oxo-2,3-dihydro-1H-pyrazole-4-carboxylic acid (3-chlorophenyl)amide
-
 Candida albicans
1.3.1.98 1,2-bis(4-chlorophenyl)-5-hydroxy-3-oxo-2,3-dihydro-1H-pyrazole-4-carboxylic acid (3-chlorophenyl)amide
-
 Enterococcus faecalis
1.3.1.98 1,2-bis(4-chlorophenyl)-5-hydroxy-3-oxo-2,3-dihydro-1H-pyrazole-4-carboxylic acid (3-chlorophenyl)amide
-
 Escherichia coli
1.3.1.98 1,2-bis(4-chlorophenyl)-5-hydroxy-3-oxo-2,3-dihydro-1H-pyrazole-4-carboxylic acid (3-chlorophenyl)amide
-
 Staphylococcus aureus
1.3.1.98 1,2-bis(4-chlorophenyl)-5-hydroxy-3-oxo-2,3-dihydro-1H-pyrazole-4-carboxylic acid (3-chlorophenyl)amide
-
 Streptococcus pneumoniae
1.3.1.98 1,2-bis(4-chlorophenyl)-5-hydroxy-3-oxo-2,3-dihydro-1H-pyrazole-4-carboxylic acid (3-trifluoromethylphenyl)amide
-
 Candida albicans
1.3.1.98 1,2-bis(4-chlorophenyl)-5-hydroxy-3-oxo-2,3-dihydro-1H-pyrazole-4-carboxylic acid (3-trifluoromethylphenyl)amide
-
 Enterococcus faecalis
1.3.1.98 1,2-bis(4-chlorophenyl)-5-hydroxy-3-oxo-2,3-dihydro-1H-pyrazole-4-carboxylic acid (3-trifluoromethylphenyl)amide
-
 Escherichia coli
1.3.1.98 1,2-bis(4-chlorophenyl)-5-hydroxy-3-oxo-2,3-dihydro-1H-pyrazole-4-carboxylic acid (3-trifluoromethylphenyl)amide
-
 Staphylococcus aureus
1.3.1.98 1,2-bis(4-chlorophenyl)-5-hydroxy-3-oxo-2,3-dihydro-1H-pyrazole-4-carboxylic acid (3-trifluoromethylphenyl)amide
-
 Streptococcus pneumoniae
1.3.1.98 1,2-bis(4-chlorophenyl)-5-hydroxy-3-oxo-2,3-dihydro-1H-pyrazole-4-carboxylic acid (4-chlorophenyl)amide
-
 Candida albicans
1.3.1.98 1,2-bis(4-chlorophenyl)-5-hydroxy-3-oxo-2,3-dihydro-1H-pyrazole-4-carboxylic acid (4-chlorophenyl)amide
-
 Enterococcus faecalis
1.3.1.98 1,2-bis(4-chlorophenyl)-5-hydroxy-3-oxo-2,3-dihydro-1H-pyrazole-4-carboxylic acid (4-chlorophenyl)amide
-
 Escherichia coli
1.3.1.98 1,2-bis(4-chlorophenyl)-5-hydroxy-3-oxo-2,3-dihydro-1H-pyrazole-4-carboxylic acid (4-chlorophenyl)amide
-
 Staphylococcus aureus
1.3.1.98 1,2-bis(4-chlorophenyl)-5-hydroxy-3-oxo-2,3-dihydro-1H-pyrazole-4-carboxylic acid (4-chlorophenyl)amide
-
 Streptococcus pneumoniae
1.3.1.98 1,2-bis(4-chlorophenyl)-5-hydroxy-3-oxo-2,3-dihydro-1H-pyrazole-4-carboxylic acid (4-cyanophenyl)amide
-
 Candida albicans
1.3.1.98 1,2-bis(4-chlorophenyl)-5-hydroxy-3-oxo-2,3-dihydro-1H-pyrazole-4-carboxylic acid (4-cyanophenyl)amide
-
 Enterococcus faecalis
1.3.1.98 1,2-bis(4-chlorophenyl)-5-hydroxy-3-oxo-2,3-dihydro-1H-pyrazole-4-carboxylic acid (4-cyanophenyl)amide
-
 Escherichia coli
1.3.1.98 1,2-bis(4-chlorophenyl)-5-hydroxy-3-oxo-2,3-dihydro-1H-pyrazole-4-carboxylic acid (4-cyanophenyl)amide
-
 Staphylococcus aureus
1.3.1.98 1,2-bis(4-chlorophenyl)-5-hydroxy-3-oxo-2,3-dihydro-1H-pyrazole-4-carboxylic acid (4-cyanophenyl)amide
-
 Streptococcus pneumoniae
1.3.1.98 1,2-bis(4-chlorophenyl)-5-hydroxy-3-oxo-2,3-dihydro-1H-pyrazole-4-carboxylic acid (4-hydroxyphenyl)amide
-
 Candida albicans
1.3.1.98 1,2-bis(4-chlorophenyl)-5-hydroxy-3-oxo-2,3-dihydro-1H-pyrazole-4-carboxylic acid (4-hydroxyphenyl)amide
-
 Enterococcus faecalis
1.3.1.98 1,2-bis(4-chlorophenyl)-5-hydroxy-3-oxo-2,3-dihydro-1H-pyrazole-4-carboxylic acid (4-hydroxyphenyl)amide
-
 Escherichia coli
1.3.1.98 1,2-bis(4-chlorophenyl)-5-hydroxy-3-oxo-2,3-dihydro-1H-pyrazole-4-carboxylic acid (4-hydroxyphenyl)amide
-
 Staphylococcus aureus
1.3.1.98 1,2-bis(4-chlorophenyl)-5-hydroxy-3-oxo-2,3-dihydro-1H-pyrazole-4-carboxylic acid (4-hydroxyphenyl)amide
-
 Streptococcus pneumoniae
1.3.1.98 1,2-bis(4-chlorophenyl)-5-hydroxy-3-oxo-2,3-dihydro-1H-pyrazole-4-carboxylic acid (4-methoxyphenyl)amide
-
 Candida albicans
1.3.1.98 1,2-bis(4-chlorophenyl)-5-hydroxy-3-oxo-2,3-dihydro-1H-pyrazole-4-carboxylic acid (4-methoxyphenyl)amide
-
 Enterococcus faecalis
1.3.1.98 1,2-bis(4-chlorophenyl)-5-hydroxy-3-oxo-2,3-dihydro-1H-pyrazole-4-carboxylic acid (4-methoxyphenyl)amide
-
 Escherichia coli
1.3.1.98 1,2-bis(4-chlorophenyl)-5-hydroxy-3-oxo-2,3-dihydro-1H-pyrazole-4-carboxylic acid (4-methoxyphenyl)amide
-
 Staphylococcus aureus
1.3.1.98 1,2-bis(4-chlorophenyl)-5-hydroxy-3-oxo-2,3-dihydro-1H-pyrazole-4-carboxylic acid (4-methoxyphenyl)amide
-
 Streptococcus pneumoniae
1.3.1.98 1,2-bis(4-chlorophenyl)-5-hydroxy-3-oxo-2,3-dihydro-1H-pyrazole-4-carboxylic acid (4-trifluoromethylphenyl)amide
-
 Candida albicans
1.3.1.98 1,2-bis(4-chlorophenyl)-5-hydroxy-3-oxo-2,3-dihydro-1H-pyrazole-4-carboxylic acid (4-trifluoromethylphenyl)amide
-
 Enterococcus faecalis
1.3.1.98 1,2-bis(4-chlorophenyl)-5-hydroxy-3-oxo-2,3-dihydro-1H-pyrazole-4-carboxylic acid (4-trifluoromethylphenyl)amide
-
 Escherichia coli
1.3.1.98 1,2-bis(4-chlorophenyl)-5-hydroxy-3-oxo-2,3-dihydro-1H-pyrazole-4-carboxylic acid (4-trifluoromethylphenyl)amide
-
 Staphylococcus aureus
1.3.1.98 1,2-bis(4-chlorophenyl)-5-hydroxy-3-oxo-2,3-dihydro-1H-pyrazole-4-carboxylic acid (4-trifluoromethylphenyl)amide
-
 Streptococcus pneumoniae
1.3.1.98 1,2-bis(4-chlorophenyl)-5-hydroxy-3-oxo-2,3-dihydro-1H-pyrazole-4-carboxylic acid 2,4-dichlorobenzylamide
-
 Candida albicans
1.3.1.98 1,2-bis(4-chlorophenyl)-5-hydroxy-3-oxo-2,3-dihydro-1H-pyrazole-4-carboxylic acid 2,4-dichlorobenzylamide
-
 Enterococcus faecalis
1.3.1.98 1,2-bis(4-chlorophenyl)-5-hydroxy-3-oxo-2,3-dihydro-1H-pyrazole-4-carboxylic acid 2,4-dichlorobenzylamide
-
 Escherichia coli
1.3.1.98 1,2-bis(4-chlorophenyl)-5-hydroxy-3-oxo-2,3-dihydro-1H-pyrazole-4-carboxylic acid 2,4-dichlorobenzylamide
-
 Staphylococcus aureus
1.3.1.98 1,2-bis(4-chlorophenyl)-5-hydroxy-3-oxo-2,3-dihydro-1H-pyrazole-4-carboxylic acid 2,4-dichlorobenzylamide
-
 Streptococcus pneumoniae
1.3.1.98 1,2-bis(4-chlorophenyl)-5-hydroxy-3-oxo-2,3-dihydro-1H-pyrazole-4-carboxylic acid 2-chlorobenzylamide
-
 Candida albicans
1.3.1.98 1,2-bis(4-chlorophenyl)-5-hydroxy-3-oxo-2,3-dihydro-1H-pyrazole-4-carboxylic acid 2-chlorobenzylamide
-
 Enterococcus faecalis
1.3.1.98 1,2-bis(4-chlorophenyl)-5-hydroxy-3-oxo-2,3-dihydro-1H-pyrazole-4-carboxylic acid 2-chlorobenzylamide
-
 Escherichia coli
1.3.1.98 1,2-bis(4-chlorophenyl)-5-hydroxy-3-oxo-2,3-dihydro-1H-pyrazole-4-carboxylic acid 2-chlorobenzylamide
-
 Staphylococcus aureus
1.3.1.98 1,2-bis(4-chlorophenyl)-5-hydroxy-3-oxo-2,3-dihydro-1H-pyrazole-4-carboxylic acid 2-chlorobenzylamide
-
 Streptococcus pneumoniae
1.3.1.98 1,2-bis(4-chlorophenyl)-5-hydroxy-3-oxo-2,3-dihydro-1H-pyrazole-4-carboxylic acid 3,4-dichlorobenzylamide
-
 Candida albicans
1.3.1.98 1,2-bis(4-chlorophenyl)-5-hydroxy-3-oxo-2,3-dihydro-1H-pyrazole-4-carboxylic acid 3,4-dichlorobenzylamide
-
 Enterococcus faecalis
1.3.1.98 1,2-bis(4-chlorophenyl)-5-hydroxy-3-oxo-2,3-dihydro-1H-pyrazole-4-carboxylic acid 3,4-dichlorobenzylamide
-
 Escherichia coli
1.3.1.98 1,2-bis(4-chlorophenyl)-5-hydroxy-3-oxo-2,3-dihydro-1H-pyrazole-4-carboxylic acid 3,4-dichlorobenzylamide
-
 Staphylococcus aureus
1.3.1.98 1,2-bis(4-chlorophenyl)-5-hydroxy-3-oxo-2,3-dihydro-1H-pyrazole-4-carboxylic acid 3,4-dichlorobenzylamide
-
 Streptococcus pneumoniae
1.3.1.98 1,2-bis(4-chlorophenyl)-5-hydroxy-3-oxo-2,3-dihydro-1H-pyrazole-4-carboxylic acid cyclohexylamide
-
 Candida albicans
1.3.1.98 1,2-bis(4-chlorophenyl)-5-hydroxy-3-oxo-2,3-dihydro-1H-pyrazole-4-carboxylic acid cyclohexylamide
-
 Enterococcus faecalis
1.3.1.98 1,2-bis(4-chlorophenyl)-5-hydroxy-3-oxo-2,3-dihydro-1H-pyrazole-4-carboxylic acid cyclohexylamide
-
 Escherichia coli
1.3.1.98 1,2-bis(4-chlorophenyl)-5-hydroxy-3-oxo-2,3-dihydro-1H-pyrazole-4-carboxylic acid cyclohexylamide
-
 Staphylococcus aureus
1.3.1.98 1,2-bis(4-chlorophenyl)-5-hydroxy-3-oxo-2,3-dihydro-1H-pyrazole-4-carboxylic acid cyclohexylamide
-
 Streptococcus pneumoniae
1.3.1.98 1,2-bis(4-chlorophenyl)-5-hydroxy-3-oxo-2,3-dihydro-1H-pyrazole-4-carboxylic acid phenethylamide
-
 Candida albicans
1.3.1.98 1,2-bis(4-chlorophenyl)-5-hydroxy-3-oxo-2,3-dihydro-1H-pyrazole-4-carboxylic acid phenethylamide
-
 Enterococcus faecalis
1.3.1.98 1,2-bis(4-chlorophenyl)-5-hydroxy-3-oxo-2,3-dihydro-1H-pyrazole-4-carboxylic acid phenethylamide
-
 Escherichia coli
1.3.1.98 1,2-bis(4-chlorophenyl)-5-hydroxy-3-oxo-2,3-dihydro-1H-pyrazole-4-carboxylic acid phenethylamide
-
 Staphylococcus aureus
1.3.1.98 1,2-bis(4-chlorophenyl)-5-hydroxy-3-oxo-2,3-dihydro-1H-pyrazole-4-carboxylic acid phenethylamide
-
 Streptococcus pneumoniae
1.3.1.98 1,2-bis(4-chlorophenyl)-5-hydroxy-3-oxo-2,3-dihydro-1H-pyrazole-4-carboxylic acid [1-(4-bromophenyl)ethyl]amide
-
 Candida albicans
1.3.1.98 1,2-bis(4-chlorophenyl)-5-hydroxy-3-oxo-2,3-dihydro-1H-pyrazole-4-carboxylic acid [1-(4-bromophenyl)ethyl]amide
-
 Enterococcus faecalis
1.3.1.98 1,2-bis(4-chlorophenyl)-5-hydroxy-3-oxo-2,3-dihydro-1H-pyrazole-4-carboxylic acid [1-(4-bromophenyl)ethyl]amide
-
 Escherichia coli
1.3.1.98 1,2-bis(4-chlorophenyl)-5-hydroxy-3-oxo-2,3-dihydro-1H-pyrazole-4-carboxylic acid [1-(4-bromophenyl)ethyl]amide
-
 Staphylococcus aureus
1.3.1.98 1,2-bis(4-chlorophenyl)-5-hydroxy-3-oxo-2,3-dihydro-1H-pyrazole-4-carboxylic acid [1-(4-bromophenyl)ethyl]amide
-
 Streptococcus pneumoniae
1.3.1.98 1,2-bis(4-chlorophenyl)-5-hydroxy-3-oxo-2,3-dihydro-1H-pyrazole-4-carboxylic acid [4(3-(dimethylamino)propylcarbamoyl)-phenyl]amide
-
 Candida albicans
1.3.1.98 1,2-bis(4-chlorophenyl)-5-hydroxy-3-oxo-2,3-dihydro-1H-pyrazole-4-carboxylic acid [4(3-(dimethylamino)propylcarbamoyl)-phenyl]amide
-
 Enterococcus faecalis
1.3.1.98 1,2-bis(4-chlorophenyl)-5-hydroxy-3-oxo-2,3-dihydro-1H-pyrazole-4-carboxylic acid [4(3-(dimethylamino)propylcarbamoyl)-phenyl]amide
-
 Escherichia coli
1.3.1.98 1,2-bis(4-chlorophenyl)-5-hydroxy-3-oxo-2,3-dihydro-1H-pyrazole-4-carboxylic acid [4(3-(dimethylamino)propylcarbamoyl)-phenyl]amide
-
 Staphylococcus aureus
1.3.1.98 1,2-bis(4-chlorophenyl)-5-hydroxy-3-oxo-2,3-dihydro-1H-pyrazole-4-carboxylic acid [4(3-(dimethylamino)propylcarbamoyl)-phenyl]amide
-
 Streptococcus pneumoniae
1.3.1.98 1,2-bis(4-chlorophenyl)-5-hydroxy-4-(4-methoxybenzoyl)-1,2-dihydropyrazol-3-one
-
 Candida albicans
1.3.1.98 1,2-bis(4-chlorophenyl)-5-hydroxy-4-(4-methoxybenzoyl)-1,2-dihydropyrazol-3-one
-
 Enterococcus faecalis
1.3.1.98 1,2-bis(4-chlorophenyl)-5-hydroxy-4-(4-methoxybenzoyl)-1,2-dihydropyrazol-3-one
-
 Escherichia coli
1.3.1.98 1,2-bis(4-chlorophenyl)-5-hydroxy-4-(4-methoxybenzoyl)-1,2-dihydropyrazol-3-one
-
 Staphylococcus aureus
1.3.1.98 1,2-bis(4-chlorophenyl)-5-hydroxy-4-(4-methoxybenzoyl)-1,2-dihydropyrazol-3-one
-
 Streptococcus pneumoniae
1.3.1.98 1,2-bis(4-chlorophenyl)-5-hydroxy-4-(4-trifluoromethoxybenzoyl)-1,2-dihydropyrazol-3-one
-
 Candida albicans
1.3.1.98 1,2-bis(4-chlorophenyl)-5-hydroxy-4-(4-trifluoromethoxybenzoyl)-1,2-dihydropyrazol-3-one
-
 Enterococcus faecalis
1.3.1.98 1,2-bis(4-chlorophenyl)-5-hydroxy-4-(4-trifluoromethoxybenzoyl)-1,2-dihydropyrazol-3-one
-
 Escherichia coli
1.3.1.98 1,2-bis(4-chlorophenyl)-5-hydroxy-4-(4-trifluoromethoxybenzoyl)-1,2-dihydropyrazol-3-one
-
 Staphylococcus aureus
1.3.1.98 1,2-bis(4-chlorophenyl)-5-hydroxy-4-(4-trifluoromethoxybenzoyl)-1,2-dihydropyrazol-3-one
-
 Streptococcus pneumoniae
1.3.1.98 1,2-bis(4-chlorophenyl)-5-hydroxy-4-(4-trifluoromethylbenzoyl)-1,2-dihydropyrazol-3-one
-
 Candida albicans
1.3.1.98 1,2-bis(4-chlorophenyl)-5-hydroxy-4-(4-trifluoromethylbenzoyl)-1,2-dihydropyrazol-3-one
-
 Enterococcus faecalis
1.3.1.98 1,2-bis(4-chlorophenyl)-5-hydroxy-4-(4-trifluoromethylbenzoyl)-1,2-dihydropyrazol-3-one
-
 Escherichia coli
1.3.1.98 1,2-bis(4-chlorophenyl)-5-hydroxy-4-(4-trifluoromethylbenzoyl)-1,2-dihydropyrazol-3-one
-
 Staphylococcus aureus
1.3.1.98 1,2-bis(4-chlorophenyl)-5-hydroxy-4-(4-trifluoromethylbenzoyl)-1,2-dihydropyrazol-3-one
-
 Streptococcus pneumoniae
1.3.1.98 1,2-bis(4-chlorophenyl)-5-hydroxy-4-(thiophene-2-carbonyl)-1,2-dihydropyrazol-3-one
-
 Candida albicans
1.3.1.98 1,2-bis(4-chlorophenyl)-5-hydroxy-4-(thiophene-2-carbonyl)-1,2-dihydropyrazol-3-one
-
 Enterococcus faecalis
1.3.1.98 1,2-bis(4-chlorophenyl)-5-hydroxy-4-(thiophene-2-carbonyl)-1,2-dihydropyrazol-3-one
-
 Escherichia coli
1.3.1.98 1,2-bis(4-chlorophenyl)-5-hydroxy-4-(thiophene-2-carbonyl)-1,2-dihydropyrazol-3-one
-
 Staphylococcus aureus
1.3.1.98 1,2-bis(4-chlorophenyl)-5-hydroxy-4-(thiophene-2-carbonyl)-1,2-dihydropyrazol-3-one
-
 Streptococcus pneumoniae
1.3.1.98 1,2-bis(4-chlorophenyl)-5-hydroxy-4-[2-(4-methoxyphenyl)acetyl]-1,2-dihydropyrazol-3-one
-
 Candida albicans
1.3.1.98 1,2-bis(4-chlorophenyl)-5-hydroxy-4-[2-(4-methoxyphenyl)acetyl]-1,2-dihydropyrazol-3-one
-
 Enterococcus faecalis
1.3.1.98 1,2-bis(4-chlorophenyl)-5-hydroxy-4-[2-(4-methoxyphenyl)acetyl]-1,2-dihydropyrazol-3-one
-
 Escherichia coli
1.3.1.98 1,2-bis(4-chlorophenyl)-5-hydroxy-4-[2-(4-methoxyphenyl)acetyl]-1,2-dihydropyrazol-3-one
-
 Staphylococcus aureus
1.3.1.98 1,2-bis(4-chlorophenyl)-5-hydroxy-4-[2-(4-methoxyphenyl)acetyl]-1,2-dihydropyrazol-3-one
-
 Streptococcus pneumoniae
1.3.1.98 1,2-bis(4-chlorophenyl)pyrazolidine-3,5-dione
-
 Candida albicans
1.3.1.98 1,2-bis(4-chlorophenyl)pyrazolidine-3,5-dione
-
 Enterococcus faecalis
1.3.1.98 1,2-bis(4-chlorophenyl)pyrazolidine-3,5-dione
-
 Escherichia coli
1.3.1.98 1,2-bis(4-chlorophenyl)pyrazolidine-3,5-dione
-
 Staphylococcus aureus
1.3.1.98 1,2-bis(4-chlorophenyl)pyrazolidine-3,5-dione
-
 Streptococcus pneumoniae
1.3.1.98 1,2-bis(4-fluorophenyl)pyrazolidine-3,5-dione
-
 Candida albicans
1.3.1.98 1,2-bis(4-fluorophenyl)pyrazolidine-3,5-dione
-
 Enterococcus faecalis
1.3.1.98 1,2-bis(4-fluorophenyl)pyrazolidine-3,5-dione
-
 Escherichia coli
1.3.1.98 1,2-bis(4-fluorophenyl)pyrazolidine-3,5-dione
-
 Staphylococcus aureus
1.3.1.98 1,2-bis(4-fluorophenyl)pyrazolidine-3,5-dione
-
 Streptococcus pneumoniae
1.3.1.98 1,2-diphenylpyrazolidine-3,5-dione slight inhibition Candida albicans
1.3.1.98 1,2-diphenylpyrazolidine-3,5-dione slight inhibition Enterococcus faecalis
1.3.1.98 1,2-diphenylpyrazolidine-3,5-dione slight inhibition Escherichia coli
1.3.1.98 1,2-diphenylpyrazolidine-3,5-dione slight inhibition Staphylococcus aureus
1.3.1.98 1,2-diphenylpyrazolidine-3,5-dione slight inhibition Streptococcus pneumoniae
1.3.1.98 4-(4-butoxybenzoyl)-1,2-bis(4-chlorophenyl)-5-hydroxy-1,2-dihydropyrazol-3-one
-
 Candida albicans
1.3.1.98 4-(4-butoxybenzoyl)-1,2-bis(4-chlorophenyl)-5-hydroxy-1,2-dihydropyrazol-3-one
-
 Enterococcus faecalis
1.3.1.98 4-(4-butoxybenzoyl)-1,2-bis(4-chlorophenyl)-5-hydroxy-1,2-dihydropyrazol-3-one
-
 Escherichia coli
1.3.1.98 4-(4-butoxybenzoyl)-1,2-bis(4-chlorophenyl)-5-hydroxy-1,2-dihydropyrazol-3-one
-
 Staphylococcus aureus
1.3.1.98 4-(4-butoxybenzoyl)-1,2-bis(4-chlorophenyl)-5-hydroxy-1,2-dihydropyrazol-3-one
-
 Streptococcus pneumoniae
1.3.1.98 4-(4-chlorobenzoyl)1,2-bis(4-chlorophenyl)-5-hydroxy-1,2-dihydropyrazol-3-one
-
 Candida albicans
1.3.1.98 4-(4-chlorobenzoyl)1,2-bis(4-chlorophenyl)-5-hydroxy-1,2-dihydropyrazol-3-one
-
 Enterococcus faecalis
1.3.1.98 4-(4-chlorobenzoyl)1,2-bis(4-chlorophenyl)-5-hydroxy-1,2-dihydropyrazol-3-one
-
 Escherichia coli
1.3.1.98 4-(4-chlorobenzoyl)1,2-bis(4-chlorophenyl)-5-hydroxy-1,2-dihydropyrazol-3-one
-
 Staphylococcus aureus
1.3.1.98 4-(4-chlorobenzoyl)1,2-bis(4-chlorophenyl)-5-hydroxy-1,2-dihydropyrazol-3-one
-
 Streptococcus pneumoniae
1.3.1.98 4-(biphenylyl-4-carbonyl)-1,2-bis(4-chlorophenyl)-5-hydroxy-1,2-dihydropyrazol-3-one
-
 Candida albicans
1.3.1.98 4-(biphenylyl-4-carbonyl)-1,2-bis(4-chlorophenyl)-5-hydroxy-1,2-dihydropyrazol-3-one
-
 Enterococcus faecalis
1.3.1.98 4-(biphenylyl-4-carbonyl)-1,2-bis(4-chlorophenyl)-5-hydroxy-1,2-dihydropyrazol-3-one
-
 Escherichia coli
1.3.1.98 4-(biphenylyl-4-carbonyl)-1,2-bis(4-chlorophenyl)-5-hydroxy-1,2-dihydropyrazol-3-one
-
 Staphylococcus aureus
1.3.1.98 4-(biphenylyl-4-carbonyl)-1,2-bis(4-chlorophenyl)-5-hydroxy-1,2-dihydropyrazol-3-one
-
 Streptococcus pneumoniae
1.3.1.98 4-[1,2-bis(4-chlorophenyl)-5-hydroxy-3-oxo-2,3-dihydro-1H-pyrazole-4-carbonyl]aminobenzoic acid
-
 Candida albicans
1.3.1.98 4-[1,2-bis(4-chlorophenyl)-5-hydroxy-3-oxo-2,3-dihydro-1H-pyrazole-4-carbonyl]aminobenzoic acid
-
 Enterococcus faecalis
1.3.1.98 4-[1,2-bis(4-chlorophenyl)-5-hydroxy-3-oxo-2,3-dihydro-1H-pyrazole-4-carbonyl]aminobenzoic acid
-
 Escherichia coli
1.3.1.98 4-[1,2-bis(4-chlorophenyl)-5-hydroxy-3-oxo-2,3-dihydro-1H-pyrazole-4-carbonyl]aminobenzoic acid
-
 Staphylococcus aureus
1.3.1.98 4-[1,2-bis(4-chlorophenyl)-5-hydroxy-3-oxo-2,3-dihydro-1H-pyrazole-4-carbonyl]aminobenzoic acid
-
 Streptococcus pneumoniae
1.3.1.98 4-[1,2-bis(4-chlorophenyl)-5-hydroxy-3-oxo-2,3-dihydro-1H-pyrazole-4-carbonyl]aminobenzoic acid ethyl ester
-
 Candida albicans
1.3.1.98 4-[1,2-bis(4-chlorophenyl)-5-hydroxy-3-oxo-2,3-dihydro-1H-pyrazole-4-carbonyl]aminobenzoic acid ethyl ester
-
 Enterococcus faecalis
1.3.1.98 4-[1,2-bis(4-chlorophenyl)-5-hydroxy-3-oxo-2,3-dihydro-1H-pyrazole-4-carbonyl]aminobenzoic acid ethyl ester
-
 Escherichia coli
1.3.1.98 4-[1,2-bis(4-chlorophenyl)-5-hydroxy-3-oxo-2,3-dihydro-1H-pyrazole-4-carbonyl]aminobenzoic acid ethyl ester
-
 Staphylococcus aureus
1.3.1.98 4-[1,2-bis(4-chlorophenyl)-5-hydroxy-3-oxo-2,3-dihydro-1H-pyrazole-4-carbonyl]aminobenzoic acid ethyl ester
-
 Streptococcus pneumoniae
1.3.1.98 5-hydroxy-3-oxo-1,2-diphenyl-2,3-dihydro-1H-pyrazole-4-carboxylic acid (4-bromophenyl)amide
-
 Candida albicans
1.3.1.98 5-hydroxy-3-oxo-1,2-diphenyl-2,3-dihydro-1H-pyrazole-4-carboxylic acid (4-bromophenyl)amide
-
 Enterococcus faecalis
1.3.1.98 5-hydroxy-3-oxo-1,2-diphenyl-2,3-dihydro-1H-pyrazole-4-carboxylic acid (4-bromophenyl)amide
-
 Escherichia coli
1.3.1.98 5-hydroxy-3-oxo-1,2-diphenyl-2,3-dihydro-1H-pyrazole-4-carboxylic acid (4-bromophenyl)amide
-
 Staphylococcus aureus
1.3.1.98 5-hydroxy-3-oxo-1,2-diphenyl-2,3-dihydro-1H-pyrazole-4-carboxylic acid (4-bromophenyl)amide
-
 Streptococcus pneumoniae
1.3.1.98 5-hydroxy-3-oxo-1,2-diphenyl-2,3-dihydro-1H-pyrazole-4-carboxylic acid (4-chlorophenyl)amide
-
 Candida albicans
1.3.1.98 5-hydroxy-3-oxo-1,2-diphenyl-2,3-dihydro-1H-pyrazole-4-carboxylic acid (4-chlorophenyl)amide
-
 Enterococcus faecalis
1.3.1.98 5-hydroxy-3-oxo-1,2-diphenyl-2,3-dihydro-1H-pyrazole-4-carboxylic acid (4-chlorophenyl)amide
-
 Escherichia coli
1.3.1.98 5-hydroxy-3-oxo-1,2-diphenyl-2,3-dihydro-1H-pyrazole-4-carboxylic acid (4-chlorophenyl)amide
-
 Staphylococcus aureus
1.3.1.98 5-hydroxy-3-oxo-1,2-diphenyl-2,3-dihydro-1H-pyrazole-4-carboxylic acid (4-chlorophenyl)amide
-
 Streptococcus pneumoniae
1.3.1.98 5-hydroxy-3-oxo-1,2-diphenyl-2,3-dihydro-1H-pyrazole-4-carboxylic acid phenylamide
-
 Candida albicans
1.3.1.98 5-hydroxy-3-oxo-1,2-diphenyl-2,3-dihydro-1H-pyrazole-4-carboxylic acid phenylamide
-
 Enterococcus faecalis
1.3.1.98 5-hydroxy-3-oxo-1,2-diphenyl-2,3-dihydro-1H-pyrazole-4-carboxylic acid phenylamide
-
 Escherichia coli
1.3.1.98 5-hydroxy-3-oxo-1,2-diphenyl-2,3-dihydro-1H-pyrazole-4-carboxylic acid phenylamide
-
 Staphylococcus aureus
1.3.1.98 5-hydroxy-3-oxo-1,2-diphenyl-2,3-dihydro-1H-pyrazole-4-carboxylic acid phenylamide
-
 Streptococcus pneumoniae
1.3.1.98 additional information maximal inhibition concentration, i.e. MIC, values, overview Candida albicans
1.3.1.98 additional information maximal inhibition concentration, i.e. MIC, values, overview Enterococcus faecalis
1.3.1.98 additional information maximal inhibition concentration, i.e. MIC, values, overview Escherichia coli
1.3.1.98 additional information maximal inhibition concentration, i.e. MIC, values, overview Staphylococcus aureus
1.3.1.98 additional information maximal inhibition concentration, i.e. MIC, values, overview Streptococcus pneumoniae

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.3.1.98 UDP-N-acetylenolpyruvylglucosamine + NADPH Staphylococcus aureus
-
 UDP-N-acetylmuramic acid + NADP+
-
 ?
1.3.1.98 UDP-N-acetylenolpyruvylglucosamine + NADPH Escherichia coli
-
 UDP-N-acetylmuramic acid + NADP+
-
 ?
1.3.1.98 UDP-N-acetylenolpyruvylglucosamine + NADPH Enterococcus faecalis
-
 UDP-N-acetylmuramic acid + NADP+
-
 ?
1.3.1.98 UDP-N-acetylenolpyruvylglucosamine + NADPH Streptococcus pneumoniae
-
 UDP-N-acetylmuramic acid + NADP+
-
 ?
1.3.1.98 UDP-N-acetylenolpyruvylglucosamine + NADPH Candida albicans
-
 UDP-N-acetylmuramic acid + NADP+
-
 ?
1.3.1.98 UDP-N-acetylenolpyruvylglucosamine + NADPH Staphylococcus aureus GC 1131
-
 UDP-N-acetylmuramic acid + NADP+
-
 ?
1.3.1.98 UDP-N-acetylenolpyruvylglucosamine + NADPH Escherichia coli GC 4560 imp
-
 UDP-N-acetylmuramic acid + NADP+
-
 ?
1.3.1.98 UDP-N-acetylenolpyruvylglucosamine + NADPH Streptococcus pneumoniae GC 1894
-
 UDP-N-acetylmuramic acid + NADP+
-
 ?
1.3.1.98 UDP-N-acetylenolpyruvylglucosamine + NADPH Enterococcus faecalis GC 2242
-
 UDP-N-acetylmuramic acid + NADP+
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
1.3.1.98 Candida albicans
-
-
-
1.3.1.98 Enterococcus faecalis
-
-
-
1.3.1.98 Enterococcus faecalis GC 2242
-
-
-
1.3.1.98 Escherichia coli
-
-
-
1.3.1.98 Escherichia coli GC 4560 imp
-
-
-
1.3.1.98 Staphylococcus aureus
-
-
-
1.3.1.98 Staphylococcus aureus GC 1131
-
-
-
1.3.1.98 Streptococcus pneumoniae
-
-
-
1.3.1.98 Streptococcus pneumoniae GC 1894
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
1.3.1.98 recombinant enzyme from strain BL21(DE3) by ammonium sulfate fractionation, hydrophobic interaction and ion exchange chromatography to homogeneity Escherichia coli

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.3.1.98 UDP-N-acetylenolpyruvylglucosamine + NADPH
-
 Staphylococcus aureus UDP-N-acetylmuramic acid + NADP+
-
 ?
1.3.1.98 UDP-N-acetylenolpyruvylglucosamine + NADPH
-
 Escherichia coli UDP-N-acetylmuramic acid + NADP+
-
 ?
1.3.1.98 UDP-N-acetylenolpyruvylglucosamine + NADPH
-
 Enterococcus faecalis UDP-N-acetylmuramic acid + NADP+
-
 ?
1.3.1.98 UDP-N-acetylenolpyruvylglucosamine + NADPH
-
 Streptococcus pneumoniae UDP-N-acetylmuramic acid + NADP+
-
 ?
1.3.1.98 UDP-N-acetylenolpyruvylglucosamine + NADPH
-
 Candida albicans UDP-N-acetylmuramic acid + NADP+
-
 ?
1.3.1.98 UDP-N-acetylenolpyruvylglucosamine + NADPH
-
 Staphylococcus aureus GC 1131 UDP-N-acetylmuramic acid + NADP+
-
 ?
1.3.1.98 UDP-N-acetylenolpyruvylglucosamine + NADPH
-
 Escherichia coli GC 4560 imp UDP-N-acetylmuramic acid + NADP+
-
 ?
1.3.1.98 UDP-N-acetylenolpyruvylglucosamine + NADPH
-
 Streptococcus pneumoniae GC 1894 UDP-N-acetylmuramic acid + NADP+
-
 ?
1.3.1.98 UDP-N-acetylenolpyruvylglucosamine + NADPH
-
 Enterococcus faecalis GC 2242 UDP-N-acetylmuramic acid + NADP+
-
 ?

Synonyms

EC Number Synonyms Comment Organism
1.3.1.98 MurB
-
 Staphylococcus aureus
1.3.1.98 MurB
-
 Escherichia coli
1.3.1.98 MurB
-
 Enterococcus faecalis
1.3.1.98 MurB
-
 Streptococcus pneumoniae
1.3.1.98 MurB
-
 Candida albicans
1.3.1.98 UDP-N-acetylenolpyruvyl glucosamine reductase
-
 Staphylococcus aureus
1.3.1.98 UDP-N-acetylenolpyruvyl glucosamine reductase
-
 Escherichia coli
1.3.1.98 UDP-N-acetylenolpyruvyl glucosamine reductase
-
 Enterococcus faecalis
1.3.1.98 UDP-N-acetylenolpyruvyl glucosamine reductase
-
 Streptococcus pneumoniae
1.3.1.98 UDP-N-acetylenolpyruvyl glucosamine reductase
-
 Candida albicans

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
1.3.1.98 8
-
 assay at Staphylococcus aureus
1.3.1.98 8
-
 assay at Escherichia coli
1.3.1.98 8
-
 assay at Enterococcus faecalis
1.3.1.98 8
-
 assay at Streptococcus pneumoniae
1.3.1.98 8
-
 assay at Candida albicans

Cofactor

EC Number Cofactor Comment Organism Structure
1.3.1.98 NADPH
-
 Staphylococcus aureus
1.3.1.98 NADPH
-
 Escherichia coli
1.3.1.98 NADPH
-
 Enterococcus faecalis
1.3.1.98 NADPH
-
 Streptococcus pneumoniae
1.3.1.98 NADPH
-
 Candida albicans