EC Number | Metals/Ions | Comment | Organism | Structure |
---|---|---|---|---|
1.8.4.10 | Iron | 4Fe-4S containing protein. Oxidation state of +2 for the 4Fe-4S cluster, with no disulfide bond in the holoenzyme | Mycobacterium tuberculosis |
EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|---|
1.8.99.2 | 28350 | - |
calculated average mass, determined on the elemental composition of the apoprotein plus the components in the metal center, assuming that all cysteines are in reduced form and the metal cluster has an oxidation state of zero | Mycobacterium tuberculosis |
1.8.99.2 | 28360 | - |
calculated from amino acid sequence | Mycobacterium tuberculosis |
1.8.99.2 | 28700 | - |
1 * 28700, ESI-FTICR mass spectrometry | Mycobacterium tuberculosis |
1.8.99.2 | 28710 | - |
ESI-FTICR mass spectrometry | Mycobacterium tuberculosis |
1.8.99.2 | 28710 | - |
theoretical value based on the chemical formula | Mycobacterium tuberculosis |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
1.8.4.10 | Mycobacterium tuberculosis | - |
recombinantly expressed in Escherichia coli | - |
1.8.99.2 | Mycobacterium tuberculosis | - |
- |
- |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
1.8.4.10 | adenosine 5'-phosphosulfate + thioredoxin | noncovalent complexes of the holoprotein with several ligands, including adenosine 5'-phosphosulfate, thioredoxin, and AMP, are investigated. AMP binds with a higher affinity to the enzyme intermediate than to the free enzyme | Mycobacterium tuberculosis | AMP + sulfite + thioredoxin disulfide | - |
? | |
1.8.99.2 | adenylyl sulfate + reduced thioredoxin | - |
Mycobacterium tuberculosis | AMP + sulfite + oxidized thioredoxin | - |
? |
EC Number | Subunits | Comment | Organism |
---|---|---|---|
1.8.99.2 | monomer | 1 * 28700, ESI-FTICR mass spectrometry | Mycobacterium tuberculosis |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
1.8.4.10 | APS reductase | - |
Mycobacterium tuberculosis |
1.8.99.2 | adenosine 5'-phosphosulfate reductase | - |
Mycobacterium tuberculosis |
1.8.99.2 | APR | - |
Mycobacterium tuberculosis |
EC Number | Cofactor | Comment | Organism | Structure |
---|---|---|---|---|
1.8.99.2 | thioredoxin | - |
Mycobacterium tuberculosis |