Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Tanizaki, M.M.
    Bothrolysin (2004), Handbook Of Proteolytic Enzymes(Barrett,A. J. ,Rawlings,N. D. ,Woessner,J. F. ,Eds. )Academic Press, 1, 657-658.
No PubMed abstract available

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.4.24.50 1,10-phenanthroline totally inhibits at 0.1 mM Bothrops jararaca
3.4.24.50 DM43 serum from opossum, inhibits the fibrinogenolytic activity of bothrolysin and forms a stable complex with it Bothrops jararaca
3.4.24.50 DTNB inhibitory, partially prevented by addition of Ca2+ Bothrops jararaca
3.4.24.50 EDTA totally inhibits at 0.1 mM Bothrops jararaca
3.4.24.50 additional information not inhibited by phosphoramidon at 0.5 mM and E-64 and its derivates Bothrops jararaca
3.4.24.50 Protein inhibitor from blood plasma of Bothrops jararaca, completely inhibits Bothrops jararaca

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
3.4.24.50 Ca2+ increases reaction velocity, half-maximum activation at 0.4 mM Bothrops jararaca

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
3.4.24.50 23000
-
-
 Bothrops jararaca

Organism

EC Number Organism UniProt Comment Textmining
3.4.24.50 Bothrops jararaca
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
3.4.24.50 by column chromatography Bothrops jararaca

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.4.24.50 venom
-
 Bothrops jararaca
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.4.24.50 angiotensin I + H2O
-
 Bothrops jararaca Asp-Arg-Val-Tyr-Ile-His-Pro + Phe-His-Leu
-
 ?
3.4.24.50 casein + H2O
-
 Bothrops jararaca ?
-
 ?
3.4.24.50 insulin B chain + H2O
-
 Bothrops jararaca FVNQ + HLCGS + HLVEA + LYLVCGERGFFYTPKA
-
 ?

Synonyms

EC Number Synonyms Comment Organism
3.4.24.50 J Protease
-
 Bothrops jararaca