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Literature summary extracted from

  • Findlay, V.J.; Townsend, D.M.; Morris, T.E.; Fraser, J.P.; He, L.; Tew, K.D.
    A novel role for human sulfiredoxin in the reversal of glutathionylation (2006), Cancer Res., 66, 6800-6806.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

EC Number Cloned (Comment) Organism
1.8.98.2 expressed in HEK293 cells and Escherichia coli Homo sapiens

Protein Variants

EC Number Protein Variants Comment Organism
1.8.98.2 C99S mutant created to show the importance of the cytosine residue in the deglutathionylation function of the protein Homo sapiens

Organism

EC Number Organism UniProt Comment Textmining
1.8.98.2 Homo sapiens Q9BYN0
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
1.8.98.2 Ni2+-NTA column chromatography Homo sapiens

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.8.98.2 peroxiredoxin-(S-hydroxy-S-oxocysteine) + ATP + 2 R-SH
-
 Homo sapiens peroxiredoxin-(S-hydroxycysteine) + ADP + phosphate + R-S-S-R
-
 ?

Synonyms

EC Number Synonyms Comment Organism
1.8.98.2 Srx1
-
 Homo sapiens
1.8.98.2 sulfiredoxin 1
-
 Homo sapiens