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Literature summary extracted from

  • Stocker, P.; Yousfi, M.; Djerridane, O.; Perrier, J.; Amziani, R.; El Boustani, S.; Moulin, A.
    Effect of flavonoids from various Mediterranean plants on enzymatic activity of intestinal carboxylesterase (2004), Biochimie, 86, 919-925.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.1.1.1 polyphenol extracts from Arenaria serpyllifolia competitive Rattus norvegicus
3.1.1.1 polyphenol extracts from Arenaria serpyllifolia competitive Sus scrofa
3.1.1.1 polyphenol extracts from Rhamnus alaternus non competitive Rattus norvegicus
3.1.1.1 polyphenol extracts from Rhamnus alaternus non competitive Sus scrofa
3.1.1.1 polyphenol extracts from Thapsia gargantica competitive Rattus norvegicus
3.1.1.1 polyphenol extracts from Thapsia gargantica competitive Sus scrofa

Organism

EC Number Organism UniProt Comment Textmining
3.1.1.1 Rattus norvegicus
-
-
-
3.1.1.1 Sus scrofa
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.1.1.1 intestine
-
Rattus norvegicus
-
3.1.1.1 intestine
-
Sus scrofa
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.1.1.1 4-nitrophenyl acetate + H2O
-
Rattus norvegicus 4-nitrophenol + acetate
-
?
3.1.1.1 4-nitrophenyl acetate + H2O
-
Sus scrofa 4-nitrophenol + acetate
-
?
3.1.1.1 methyl butanoate + H2O
-
Rattus norvegicus methanol + butanoate
-
?
3.1.1.1 methyl butanoate + H2O
-
Sus scrofa methanol + butanoate
-
?
3.1.1.1 tributyrin + H2O
-
Rattus norvegicus ?
-
?
3.1.1.1 tributyrin + H2O
-
Sus scrofa ?
-
?

Ki Value [mM]

EC Number Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
3.1.1.1 0.008
-
polyphenol extracts from Arenaria serpyllifolia pH 7.4, 37°C Sus scrofa
3.1.1.1 0.012
-
polyphenol extracts from Thapsia gargantica pH 7.4, 37°C Sus scrofa
3.1.1.1 0.015
-
polyphenol extracts from Arenaria serpyllifolia pH 7.4, 37°C Rattus norvegicus
3.1.1.1 0.017
-
polyphenol extracts from Thapsia gargantica pH 7.4, 37°C Rattus norvegicus
3.1.1.1 0.024
-
polyphenol extracts from Rhamnus alaternus pH 7.4, 37°C Sus scrofa
3.1.1.1 0.034
-
polyphenol extracts from Rhamnus alaternus pH 7.4, 37°C Rattus norvegicus