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Literature summary extracted from

  • George, R.L.; Huang, W.; Naggar, H.A.; Smith, S.B.; Ganapathy, V.
    Transport of N-acetylaspartate via murine sodium/dicarboxylate cotransporter NaDC3 and expression of this transporter and aspartoacylase II in ocular tissues in mouse (2004), Biochim. Biophys. Acta, 1690, 63-69.
    View publication on PubMed

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.5.1.15 additional information Mus musculus the enzyme functions in concert with the plasma membrane transporter NaDC3, that specifically transports N-acetylaspartic acid into the cell ?
-
 ?
3.5.1.15 N-acetylaspartic acid + H2O Mus musculus enzyme deficiency, due to mutations of aspartoacylase II, causes the Canavan disease, which is associated with optical neuropathy L-asparatate + acetate
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
3.5.1.15 Mus musculus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.5.1.15 ciliary body
-
 Mus musculus
-
3.5.1.15 eye ocular tissue, enzyme expression pattern Mus musculus
-
3.5.1.15 iris
-
 Mus musculus
-
3.5.1.15 lens
-
 Mus musculus
-
3.5.1.15 additional information co-localization with plasma membrane transporter NaDC3 in the optic system, in situ hybridization, overview Mus musculus
-
3.5.1.15 retina
-
 Mus musculus
-
3.5.1.15 retinal pigment epithelium
-
 Mus musculus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.5.1.15 additional information the enzyme functions in concert with the plasma membrane transporter NaDC3, that specifically transports N-acetylaspartic acid into the cell Mus musculus ?
-
 ?
3.5.1.15 N-acetylaspartic acid + H2O
-
 Mus musculus L-asparatate + acetate
-
 ?
3.5.1.15 N-acetylaspartic acid + H2O enzyme deficiency, due to mutations of aspartoacylase II, causes the Canavan disease, which is associated with optical neuropathy Mus musculus L-asparatate + acetate
-
 ?

Synonyms

EC Number Synonyms Comment Organism
3.5.1.15 aspartoacylase II
-
 Mus musculus