EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
4.2.1.10 | (1R,4S,5R)-3,3-difluoro-1,4,5-trihydroxycyclohexane-1-carboxylic acid | inhibitor is selective for the type II dehydroquinase over the type I dehydroquinase | Mycobacterium tuberculosis | |
4.2.1.10 | (1R,4S,5R)-3,3-difluoro-1,4,5-trihydroxycyclohexane-1-carboxylic acid | - |
Salmonella enterica subsp. enterica serovar Typhi | |
4.2.1.10 | (1R,4S,5R)-3,3-difluoro-1,4,5-trihydroxycyclohexane-1-carboxylic acid | inhibitor is selective for the type II dehydroquinase over the type I dehydroquinase | Streptomyces coelicolor | |
4.2.1.10 | (1R,4S,5R)-3-fluoro-1,4,5-trihydroxy-2-cyclohexene-1-carboxylic acid | inhibitor is selective for the type II dehydroquinase over the type I dehydroquinase | Mycobacterium tuberculosis | |
4.2.1.10 | (1R,4S,5R)-3-fluoro-1,4,5-trihydroxy-2-cyclohexene-1-carboxylic acid | - |
Salmonella enterica subsp. enterica serovar Typhi | |
4.2.1.10 | (1R,4S,5R)-3-fluoro-1,4,5-trihydroxy-2-cyclohexene-1-carboxylic acid | inhibitor is selective for the type II dehydroquinase over the type I dehydroquinase | Streptomyces coelicolor |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
4.2.1.10 | Mycobacterium tuberculosis | P9WPX7 | - |
- |
4.2.1.10 | Mycobacterium tuberculosis H37Rv | P9WPX7 | - |
- |
4.2.1.10 | Salmonella enterica subsp. enterica serovar Typhi | - |
- |
- |
4.2.1.10 | Streptomyces coelicolor | P15474 | - |
- |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
4.2.1.10 | Type I dehydroquinase | - |
Salmonella enterica subsp. enterica serovar Typhi |
4.2.1.10 | Type II dehydroquinase | - |
Streptomyces coelicolor |
4.2.1.10 | Type II dehydroquinase | - |
Mycobacterium tuberculosis |
EC Number | Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|---|
4.2.1.10 | 0.01 | - |
(1R,4S,5R)-3-fluoro-1,4,5-trihydroxy-2-cyclohexene-1-carboxylic acid | - |
Mycobacterium tuberculosis | |
4.2.1.10 | 0.015 | - |
(1R,4S,5R)-3-fluoro-1,4,5-trihydroxy-2-cyclohexene-1-carboxylic acid | - |
Streptomyces coelicolor | |
4.2.1.10 | 0.7 | - |
(1R,4S,5R)-3,3-difluoro-1,4,5-trihydroxycyclohexane-1-carboxylic acid | - |
Streptomyces coelicolor | |
4.2.1.10 | 0.7 | - |
(1R,4S,5R)-3,3-difluoro-1,4,5-trihydroxycyclohexane-1-carboxylic acid | - |
Mycobacterium tuberculosis | |
4.2.1.10 | 1.5 | - |
(1R,4S,5R)-3-fluoro-1,4,5-trihydroxy-2-cyclohexene-1-carboxylic acid | - |
Salmonella enterica subsp. enterica serovar Typhi | |
4.2.1.10 | 8 | - |
(1R,4S,5R)-3,3-difluoro-1,4,5-trihydroxycyclohexane-1-carboxylic acid | - |
Salmonella enterica subsp. enterica serovar Typhi |