EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
4.2.1.10 | (1R,4R,5R)-1,4,5-trihydroxycyclohex-2-ene-1-carboxylic acid | - |
Aspergillus nidulans | |
4.2.1.10 | (1R,4R,5R)-1,4,5-trihydroxycyclohex-2-ene-1-carboxylic acid | - |
Mycobacterium tuberculosis | |
4.2.1.10 | (1R,4R,5R)-1,4,5-trihydroxycyclohex-2-ene-1-carboxylic acid | - |
Salmonella enterica subsp. enterica serovar Typhimurium | |
4.2.1.10 | (1R,4R,5R)-1,4,5-trihydroxycyclohex-2-ene-1-carboxylic acid | - |
Streptomyces coelicolor | |
4.2.1.10 | (1S,3R,4R)-1,3,4-trihydroxy-5-methylenecyclohexanecarboxylic acid | - |
Aspergillus nidulans | |
4.2.1.10 | (1S,3R,4R)-1,3,4-trihydroxy-5-methylenecyclohexanecarboxylic acid | - |
Mycobacterium tuberculosis | |
4.2.1.10 | (1S,3R,4R)-1,3,4-trihydroxy-5-methylenecyclohexanecarboxylic acid | - |
Streptomyces coelicolor | |
4.2.1.10 | (1S,3R,4R)-1,3,4-trihydroxycyclohexanecarboxylic acid | - |
Aspergillus nidulans | |
4.2.1.10 | (1S,3R,4R)-1,3,4-trihydroxycyclohexanecarboxylic acid | - |
Mycobacterium tuberculosis | |
4.2.1.10 | (1S,3R,4R)-1,3,4-trihydroxycyclohexanecarboxylic acid | - |
Salmonella enterica subsp. enterica serovar Typhimurium | |
4.2.1.10 | (1S,3R,4R)-1,3,4-trihydroxycyclohexanecarboxylic acid | - |
Streptomyces coelicolor | |
4.2.1.10 | (1S,3R,4R,5E)-1,3,4-trihydroxy-5-(methylimino)cyclohexanecarboxylic acid | - |
Aspergillus nidulans | |
4.2.1.10 | (1S,3R,4R,5E)-1,3,4-trihydroxy-5-(methylimino)cyclohexanecarboxylic acid | - |
Mycobacterium tuberculosis | |
4.2.1.10 | (1S,3R,4R,5E)-1,3,4-trihydroxy-5-(methylimino)cyclohexanecarboxylic acid | - |
Streptomyces coelicolor | |
4.2.1.10 | additional information | Ki-values for (1S,3R,4R,5E)-1,3,4-trihydroxy-5-(methylimino)cyclohexanecarboxylic acid and (1S,3R,4R)-1,3,4-trihydroxy-5-methylenecyclohexanecarboxylic acid are above 25 mM | Salmonella enterica subsp. enterica serovar Typhimurium |
EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|---|
4.2.1.10 | 0.018 | - |
dehydroquinate | - |
Salmonella enterica subsp. enterica serovar Typhimurium | |
4.2.1.10 | 0.064 | - |
dehydroquinate | - |
Mycobacterium tuberculosis | |
4.2.1.10 | 0.15 | - |
dehydroquinate | - |
Aspergillus nidulans | |
4.2.1.10 | 0.65 | - |
dehydroquinate | - |
Streptomyces coelicolor |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
4.2.1.10 | Aspergillus nidulans | - |
- |
- |
4.2.1.10 | Mycobacterium tuberculosis | - |
- |
- |
4.2.1.10 | Salmonella enterica subsp. enterica serovar Typhimurium | - |
- |
- |
4.2.1.10 | Streptomyces coelicolor | - |
- |
- |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
4.2.1.10 | 3-dehydroquinate | - |
Salmonella enterica subsp. enterica serovar Typhimurium | 3-dehydroshikimate + H2O | - |
? | |
4.2.1.10 | 3-dehydroquinate | - |
Aspergillus nidulans | 3-dehydroshikimate + H2O | - |
? | |
4.2.1.10 | 3-dehydroquinate | - |
Mycobacterium tuberculosis | 3-dehydroshikimate + H2O | - |
? | |
4.2.1.10 | 3-dehydroquinate | - |
Streptomyces coelicolor | 3-dehydroshikimate + H2O | - |
? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
4.2.1.10 | Type I dehydroquinase | - |
Salmonella enterica subsp. enterica serovar Typhimurium |
4.2.1.10 | Type II dehydroquinase | - |
Aspergillus nidulans |
4.2.1.10 | Type II dehydroquinase | - |
Mycobacterium tuberculosis |
4.2.1.10 | Type II dehydroquinase | - |
Streptomyces coelicolor |
EC Number | Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|---|
4.2.1.10 | additional information | - |
additional information | Ki-values for (1S,3R,4R,5E)-1,3,4-trihydroxy-5-(methylimino)cyclohexanecarboxylic acid and (1S,3R,4R)-1,3,4-trihydroxy-5-methylenecyclohexanecarboxylic acid are above 25 mM | Salmonella enterica subsp. enterica serovar Typhimurium | |
4.2.1.10 | 0.015 | - |
(1S,3R,4R)-1,3,4-trihydroxy-5-methylenecyclohexanecarboxylic acid | - |
Aspergillus nidulans | |
4.2.1.10 | 0.02 | - |
(1S,3R,4R)-1,3,4-trihydroxy-5-methylenecyclohexanecarboxylic acid | - |
Mycobacterium tuberculosis | |
4.2.1.10 | 0.03 | - |
(1R,4R,5R)-1,4,5-trihydroxycyclohex-2-ene-1-carboxylic acid | - |
Streptomyces coelicolor | |
4.2.1.10 | 0.06 | - |
(1R,4R,5R)-1,4,5-trihydroxycyclohex-2-ene-1-carboxylic acid | - |
Aspergillus nidulans | |
4.2.1.10 | 0.2 | - |
(1R,4R,5R)-1,4,5-trihydroxycyclohex-2-ene-1-carboxylic acid | - |
Mycobacterium tuberculosis | |
4.2.1.10 | 0.5 | - |
(1S,3R,4R)-1,3,4-trihydroxy-5-methylenecyclohexanecarboxylic acid | - |
Streptomyces coelicolor | |
4.2.1.10 | 0.6 | - |
(1S,3R,4R)-1,3,4-trihydroxycyclohexanecarboxylic acid | - |
Streptomyces coelicolor | |
4.2.1.10 | 0.7 | - |
(1S,3R,4R,5E)-1,3,4-trihydroxy-5-(methylimino)cyclohexanecarboxylic acid | - |
Mycobacterium tuberculosis | |
4.2.1.10 | 1.2 | - |
(1S,3R,4R)-1,3,4-trihydroxycyclohexanecarboxylic acid | - |
Mycobacterium tuberculosis | |
4.2.1.10 | 1.5 | - |
(1S,3R,4R)-1,3,4-trihydroxycyclohexanecarboxylic acid | - |
Aspergillus nidulans | |
4.2.1.10 | 2.2 | - |
(1S,3R,4R,5E)-1,3,4-trihydroxy-5-(methylimino)cyclohexanecarboxylic acid | - |
Aspergillus nidulans | |
4.2.1.10 | 2.5 | - |
(1S,3R,4R,5E)-1,3,4-trihydroxy-5-(methylimino)cyclohexanecarboxylic acid | - |
Streptomyces coelicolor | |
4.2.1.10 | 3 | - |
(1R,4R,5R)-1,4,5-trihydroxycyclohex-2-ene-1-carboxylic acid | - |
Salmonella enterica subsp. enterica serovar Typhimurium | |
4.2.1.10 | 4.5 | - |
(1S,3R,4R)-1,3,4-trihydroxycyclohexanecarboxylic acid | - |
Salmonella enterica subsp. enterica serovar Typhimurium |