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Literature summary extracted from

  • Albert, A.P.; Piper, A.S.; Large, W.A.
    Role of phospholipase D and diacylglycerol in activating constitutive TRPC-like cation channels in rabbit ear artery myocytes (2005), J. Physiol., 566, 769-780.
    View publication on PubMedView publication on EuropePMC

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.1.4.4 butan-1-ol
-
 Oryctolagus cuniculus
3.1.4.4 C2 ceramide
-
 Oryctolagus cuniculus

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.1.4.4 additional information Oryctolagus cuniculus constitutive cation channel activity in ear artery myocytes is mediated by diacylglycerol which is generated by phosphatidylcholine-phospholipase D via phosphatidic acid which represents a novel activation pathway of cation channels in vascular myocytes ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
3.1.4.4 Oryctolagus cuniculus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.1.4.4 myocyte ear artery myocyte Oryctolagus cuniculus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.1.4.4 additional information constitutive cation channel activity in ear artery myocytes is mediated by diacylglycerol which is generated by phosphatidylcholine-phospholipase D via phosphatidic acid which represents a novel activation pathway of cation channels in vascular myocytes Oryctolagus cuniculus ?
-
 ?
3.1.4.4 phosphatidylcholine + H2O
-
 Oryctolagus cuniculus 1,2-diacylglycerophosphate + choline
-
 ?