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Literature summary extracted from
- Cytoplasmic carbonic anhydrase isozymes in rainbow trout Oncorhynchus mykiss: comparative physiology and molecular evolution (2005), J. Exp. Biol., 208, 1951-1961.
Inhibitors
| EC Number | Inhibitors | Comment | Organism | Structure |
|---|---|---|---|---|
| 4.2.1.1 | acetazolamide | - |
Oncorhynchus mykiss |  |
| 4.2.1.1 | Cl- | - |
Oncorhynchus mykiss | |
KM Value [mM]
| EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|---|
| 4.2.1.1 | 8.72 | - |
CO2 | - |
Oncorhynchus mykiss | |
| 4.2.1.1 | 23.26 | - |
CO2 | - |
Oncorhynchus mykiss | |
Localization
| EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 4.2.1.1 | Oncorhynchus mykiss | Q6R4A2 | - |
- |
| 4.2.1.1 | Oncorhynchus mykiss | Q7T2K6 | - |
- |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 4.2.1.1 | erythrocyte | - |
Oncorhynchus mykiss | - |
| 4.2.1.1 | erythrocyte | induction of anemia causes 30-60fold increase in anaemic animals | Oncorhynchus mykiss | - |
| 4.2.1.1 | gill | - |
Oncorhynchus mykiss | - |
| 4.2.1.1 | additional information | unlike isoenzyme TCAb, isoenzyme TCAc lacks tissue specificity and may be expressed in the cytoplasm of all cells | Oncorhynchus mykiss | - |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 4.2.1.1 | CO2 + H2O | - |
Oncorhynchus mykiss | H2CO3 | - |
? | |
Synonyms
| EC Number | Synonyms | Comment | Organism |
|---|---|---|---|
| 4.2.1.1 | carbonic anhydrase 2 | - |
Oncorhynchus mykiss |
| 4.2.1.1 | cytoplasmic carbonic anhydrase | - |
Oncorhynchus mykiss |
| 4.2.1.1 | erythrocyte carbonic anhydrase | - |
Oncorhynchus mykiss |
| 4.2.1.1 | TCAb | - |
Oncorhynchus mykiss |
| 4.2.1.1 | TCAc | - |
Oncorhynchus mykiss |
Turnover Number [1/s]
| EC Number | Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|---|
| 4.2.1.1 | 89000 | - |
CO2 | - |
Oncorhynchus mykiss | |
| 4.2.1.1 | 302800 | - |
CO2 | - |
Oncorhynchus mykiss | |
Ki Value [mM]
| EC Number | Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
|---|---|---|---|---|---|---|
| 4.2.1.1 | 0.00000121 | - |
acetazolamide | - |
Oncorhynchus mykiss | |
| 4.2.1.1 | 0.00000134 | - |
acetazolamide | - |
Oncorhynchus mykiss | |
| 4.2.1.1 | 0.00006134 | - |
Cl- | - |
Oncorhynchus mykiss | |
| 4.2.1.1 | 0.00006203 | - |
Cl- | - |
Oncorhynchus mykiss | |
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