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Literature summary extracted from

  • Agirregoitia, N.; Laiz-Carrion, R.; Varona, A.; Rio, M.P.; Mancera, J.M.; Irazusta, J.
    Distribution of peptidase activity in teleost and rat tissues (2005), J. Comp. Physiol. B, 175, 433-444.
    View publication on PubMed

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
3.4.11.2 extracellular plasma Rattus norvegicus
-
-
3.4.11.2 extracellular plasma Oncorhynchus mykiss
-
-
3.4.11.2 extracellular plasma Sparus aurata
-
-
3.4.11.2 soluble intracellular Rattus norvegicus
-
-
3.4.11.2 soluble intracellular Oncorhynchus mykiss
-
-
3.4.11.2 soluble intracellular Sparus aurata
-
-
3.4.11.6 extracellular plasma Rattus norvegicus
-
-
3.4.11.6 extracellular plasma Oncorhynchus mykiss
-
-
3.4.11.6 extracellular plasma Sparus aurata
-
-
3.4.11.6 soluble intracellular Rattus norvegicus
-
-
3.4.11.6 soluble intracellular Oncorhynchus mykiss
-
-
3.4.11.6 soluble intracellular Sparus aurata
-
-
3.4.11.7 extracellular plasma Rattus norvegicus
-
-
3.4.11.7 extracellular plasma Oncorhynchus mykiss
-
-
3.4.11.7 extracellular plasma Sparus aurata
-
-
3.4.11.7 membrane intracellular Rattus norvegicus 16020
-
3.4.11.7 membrane intracellular Oncorhynchus mykiss 16020
-
3.4.11.7 membrane intracellular Sparus aurata 16020
-
3.4.11.7 soluble intracellular Rattus norvegicus
-
-
3.4.11.7 soluble intracellular Oncorhynchus mykiss
-
-
3.4.11.7 soluble intracellular Sparus aurata
-
-

Organism

EC Number Organism UniProt Comment Textmining
3.4.11.2 Oncorhynchus mykiss
-
 rainbow trout
-
3.4.11.2 Rattus norvegicus
-
 male sprague-dawley rats
-
3.4.11.2 Sparus aurata
-
 gilthead sea bream
-
3.4.11.6 Oncorhynchus mykiss
-
 rainbow trout
-
3.4.11.6 Rattus norvegicus
-
 male sprague-dawley rats
-
3.4.11.6 Sparus aurata
-
 male gilthead sea bream
-
3.4.11.7 Oncorhynchus mykiss
-
 rainbow trout
-
3.4.11.7 Rattus norvegicus
-
 male sprague-dawley rats
-
3.4.11.7 Sparus aurata
-
 gilthead sea bream
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.4.11.2 blood plasma
-
 Rattus norvegicus
-
3.4.11.2 blood plasma
-
 Oncorhynchus mykiss
-
3.4.11.2 blood plasma
-
 Sparus aurata
-
3.4.11.2 brain cortex and anterior brain, striatum and middle brain, posterior brain, low enzyme activity Rattus norvegicus
-
3.4.11.2 brain cortex and anterior brain, striatum and middle brain, posterior brain, low enzyme activity Oncorhynchus mykiss
-
3.4.11.2 brain cortex and anterior brain, striatum and middle brain, posterior brain, low enzyme activity Sparus aurata
-
3.4.11.2 cerebellum low enzyme activity Rattus norvegicus
-
3.4.11.2 cerebellum low enzyme activity Oncorhynchus mykiss
-
3.4.11.2 cerebellum low enzyme activity Sparus aurata
-
3.4.11.2 gill high enzyme activity Oncorhynchus mykiss
-
3.4.11.2 gill high enzyme activity Sparus aurata
-
3.4.11.2 kidney highest enzyme activity Rattus norvegicus
-
3.4.11.2 kidney high enzyme activity Oncorhynchus mykiss
-
3.4.11.2 kidney high enzyme activity Sparus aurata
-
3.4.11.2 lung high enzyme activity Rattus norvegicus
-
3.4.11.2 additional information tissue distribution of enzyme activity, overview Rattus norvegicus
-
3.4.11.2 additional information tissue distribution of enzyme activity, overview Oncorhynchus mykiss
-
3.4.11.2 additional information tissue distribution of enzyme activity, overview Sparus aurata
-
3.4.11.2 pituitary gland
-
 Rattus norvegicus
-
3.4.11.2 pituitary gland
-
 Oncorhynchus mykiss
-
3.4.11.2 pituitary gland
-
 Sparus aurata
-
3.4.11.6 blood plasma
-
 Rattus norvegicus
-
3.4.11.6 blood plasma
-
 Oncorhynchus mykiss
-
3.4.11.6 blood plasma
-
 Sparus aurata
-
3.4.11.6 brain cortex and anterior brain, striatum and middle brain, posterior brain Rattus norvegicus
-
3.4.11.6 brain cortex and anterior brain, striatum and middle brain, posterior brain Oncorhynchus mykiss
-
3.4.11.6 brain cortex and anterior brain, striatum and middle brain, posterior brain Sparus aurata
-
3.4.11.6 cerebellum
-
 Rattus norvegicus
-
3.4.11.6 cerebellum
-
 Oncorhynchus mykiss
-
3.4.11.6 cerebellum
-
 Sparus aurata
-
3.4.11.6 gill
-
 Oncorhynchus mykiss
-
3.4.11.6 gill
-
 Sparus aurata
-
3.4.11.6 kidney
-
 Rattus norvegicus
-
3.4.11.6 kidney
-
 Oncorhynchus mykiss
-
3.4.11.6 kidney
-
 Sparus aurata
-
3.4.11.6 lung
-
 Rattus norvegicus
-
3.4.11.6 additional information tissue distribution of enzyme activity, overview Rattus norvegicus
-
3.4.11.6 additional information tissue distribution of enzyme activity, overview Oncorhynchus mykiss
-
3.4.11.6 additional information tissue distribution of enzyme activity, overview Sparus aurata
-
3.4.11.6 pituitary gland
-
 Rattus norvegicus
-
3.4.11.6 pituitary gland
-
 Oncorhynchus mykiss
-
3.4.11.6 pituitary gland
-
 Sparus aurata
-
3.4.11.7 blood plasma
-
 Rattus norvegicus
-
3.4.11.7 blood plasma
-
 Oncorhynchus mykiss
-
3.4.11.7 blood plasma
-
 Sparus aurata
-
3.4.11.7 brain cortex
-
 Rattus norvegicus
-
3.4.11.7 brain cortex
-
 Oncorhynchus mykiss
-
3.4.11.7 brain cortex
-
 Sparus aurata
-
3.4.11.7 cerebellum
-
 Rattus norvegicus
-
3.4.11.7 cerebellum
-
 Oncorhynchus mykiss
-
3.4.11.7 cerebellum
-
 Sparus aurata
-
3.4.11.7 corpus striatum
-
 Rattus norvegicus
-
3.4.11.7 corpus striatum
-
 Oncorhynchus mykiss
-
3.4.11.7 corpus striatum
-
 Sparus aurata
-
3.4.11.7 forebrain
-
 Rattus norvegicus
-
3.4.11.7 forebrain
-
 Oncorhynchus mykiss
-
3.4.11.7 forebrain
-
 Sparus aurata
-
3.4.11.7 gill
-
 Oncorhynchus mykiss
-
3.4.11.7 gill
-
 Sparus aurata
-
3.4.11.7 hindbrain
-
 Rattus norvegicus
-
3.4.11.7 hindbrain
-
 Oncorhynchus mykiss
-
3.4.11.7 hindbrain
-
 Sparus aurata
-
3.4.11.7 kidney
-
 Rattus norvegicus
-
3.4.11.7 kidney
-
 Oncorhynchus mykiss
-
3.4.11.7 kidney
-
 Sparus aurata
-
3.4.11.7 lung
-
 Rattus norvegicus
-
3.4.11.7 midbrain
-
 Rattus norvegicus
-
3.4.11.7 midbrain
-
 Oncorhynchus mykiss
-
3.4.11.7 midbrain
-
 Sparus aurata
-
3.4.11.7 additional information tissue distribution of soluble and membrane enzyme activity, overview Rattus norvegicus
-
3.4.11.7 additional information tissue distribution of soluble and membrane enzyme activity, overview Oncorhynchus mykiss
-
3.4.11.7 additional information tissue distribution of soluble and membrane enzyme activity, overview Sparus aurata
-
3.4.11.7 pituitary gland
-
 Rattus norvegicus
-
3.4.11.7 pituitary gland
-
 Oncorhynchus mykiss
-
3.4.11.7 pituitary gland
-
 Sparus aurata
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
3.4.11.2 0.00051
-
 plasma enzyme, 20°C Rattus norvegicus
3.4.11.2 0.0016
-
 plasma enzyme, 20°C Oncorhynchus mykiss
3.4.11.2 0.0017
-
 plasma enzyme, 37°C Rattus norvegicus
3.4.11.2 0.0033
-
 plasma enzyme, 37°C Oncorhynchus mykiss
3.4.11.2 0.0043
-
 plasma enzyme, 20°C Sparus aurata
3.4.11.2 0.0081
-
 plasma enzyme, 37°C Sparus aurata
3.4.11.6 0.00011
-
 plasma enzyme, 37°C Oncorhynchus mykiss
3.4.11.6 0.00012
-
 plasma enzyme, 20°C Oncorhynchus mykiss
3.4.11.6 0.0003
-
 plasma enzyme, 20°C Rattus norvegicus
3.4.11.6 0.00031
-
 plasma enzyme, 20°C Sparus aurata
3.4.11.6 0.00082
-
 plasma enzyme, 37°C Sparus aurata
3.4.11.6 0.0011
-
 plasma enzyme, 37°C Rattus norvegicus
3.4.11.7 0.000014
-
 plasma enzyme, 20°C Rattus norvegicus
3.4.11.7 0.000028
-
 plasma enzyme, 37°C Rattus norvegicus
3.4.11.7 0.000046
-
 plasma enzyme, 37°C Oncorhynchus mykiss
3.4.11.7 0.00006
-
 plasma enzyme, 20°C Oncorhynchus mykiss
3.4.11.7 0.000069
-
 plasma enzyme, 20°C Sparus aurata
3.4.11.7 0.00007
-
 plasma enzyme, 37°C Sparus aurata

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.4.11.2 L-Ala-2-naphthylamide + H2O
-
 Rattus norvegicus L-Ala + 2-naphthylamine
-
 ?
3.4.11.2 L-Ala-2-naphthylamide + H2O
-
 Oncorhynchus mykiss L-Ala + 2-naphthylamine
-
 ?
3.4.11.2 L-Ala-2-naphthylamide + H2O
-
 Sparus aurata L-Ala + 2-naphthylamine
-
 ?
3.4.11.6 L-Arg-2-naphthylamide + H2O
-
 Rattus norvegicus L-Arg + 2-naphthylamine
-
 ?
3.4.11.6 L-Arg-2-naphthylamide + H2O
-
 Oncorhynchus mykiss L-Arg + 2-naphthylamine
-
 ?
3.4.11.6 L-Arg-2-naphthylamide + H2O
-
 Sparus aurata L-Arg + 2-naphthylamine
-
 ?
3.4.11.7 L-Arg-2-naphthylamide + H2O
-
 Rattus norvegicus L-Arg + 2-naphthylamine
-
 ?
3.4.11.7 L-Arg-2-naphthylamide + H2O
-
 Oncorhynchus mykiss L-Arg + 2-naphthylamine
-
 ?
3.4.11.7 L-Arg-2-naphthylamide + H2O
-
 Sparus aurata L-Arg + 2-naphthylamine
-
 ?

Synonyms

EC Number Synonyms Comment Organism
3.4.11.2 aminopeptidase N
-
 Rattus norvegicus
3.4.11.2 aminopeptidase N
-
 Oncorhynchus mykiss
3.4.11.2 aminopeptidase N
-
 Sparus aurata
3.4.11.2 APN
-
 Rattus norvegicus
3.4.11.2 APN
-
 Oncorhynchus mykiss
3.4.11.2 APN
-
 Sparus aurata
3.4.11.2 basic aminopeptidase
-
 Rattus norvegicus
3.4.11.2 basic aminopeptidase
-
 Oncorhynchus mykiss
3.4.11.2 basic aminopeptidase
-
 Sparus aurata
3.4.11.7 acid aminopeptidase
-
 Rattus norvegicus
3.4.11.7 acid aminopeptidase
-
 Oncorhynchus mykiss
3.4.11.7 acid aminopeptidase
-
 Sparus aurata
3.4.11.7 APA
-
 Rattus norvegicus
3.4.11.7 APA
-
 Oncorhynchus mykiss
3.4.11.7 APA
-
 Sparus aurata

Temperature Range [°C]

EC Number Temperature Minimum [°C] Temperature Maximum [°C] Comment Organism
3.4.11.2 20 37 higher activity at 37°C Rattus norvegicus
3.4.11.2 20 37 higher activity at 37°C Oncorhynchus mykiss
3.4.11.2 20 37 higher activity at 37°C Sparus aurata
3.4.11.6 20 37 higher activity at 20°C Oncorhynchus mykiss
3.4.11.6 20 37 higher activity at 37°C Rattus norvegicus
3.4.11.6 20 37 higher activity at 37°C Sparus aurata
3.4.11.7 20 37 higher activity at 20°C Oncorhynchus mykiss
3.4.11.7 20 37 higher activity at 37°C Rattus norvegicus
3.4.11.7 20 37 similar activity at 20°C and 37°C Sparus aurata