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Literature summary extracted from

  • Shi, G.W.; Chen, J.; Concepcion, F.; Motamedchaboki, K.; Marjoram, P.; Langen, R.
    Light causes phosphorylation of nonactivated visual pigments in intact mouse rod photoreceptor cells (2005), J. Biol. Chem., 280, 41184-41191.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
2.7.11.14 light stimulates rhodopsin activation by phosphorylation Mus musculus

Protein Variants

EC Number Protein Variants Comment Organism
2.7.11.14 additional information construction of transgenic mouse photoreceptor cells overexpressing the human S opsin mutant K296E still show the trans-phosphorylation phenomenon and phosphorylation of nonactivated rhodopsin, overview Mus musculus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.7.11.14 membrane
-
 Mus musculus 16020
-

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.7.11.14 ATP + rhodopsin Mus musculus the enzyme phosphorylates activated rhodopsin, light causes phosphorylation of nonactivated rhodopsin in intact rod photoreceptor cells ADP + phosphorhodopsin
-
 ?
2.7.11.14 additional information Mus musculus dark-adapted retina rhodopsin is also phosphorylated in transgenic photoreceptor cells overexpressing the human S opsin mutant K296E ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.7.11.14 Mus musculus
-
-
-

Reaction

EC Number Reaction Comment Organism Reaction ID
2.7.11.14 ATP + rhodopsin = ADP + phosphorhodopsin molecular mechanism of trans-phosphorylation Mus musculus
a

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.7.11.14 photoreceptor
-
 Mus musculus
-
2.7.11.14 retina
-
 Mus musculus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.11.14 ATP + rhodopsin
-
 Mus musculus ADP + phosphorhodopsin
-
 ?
2.7.11.14 ATP + rhodopsin the enzyme phosphorylates activated rhodopsin, light causes phosphorylation of nonactivated rhodopsin in intact rod photoreceptor cells Mus musculus ADP + phosphorhodopsin
-
 ?
2.7.11.14 ATP + S opsin trans-phosphorylation is induced by activated rhodopsin Mus musculus ADP + phosphorylated S opsin
-
 ?
2.7.11.14 additional information dark-adapted retina rhodopsin is also phosphorylated in transgenic photoreceptor cells overexpressing the human S opsin mutant K296E Mus musculus ?
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.7.11.14 More the enzyme belongs to the G-protein coupled receptor kinase family Mus musculus

Cofactor

EC Number Cofactor Comment Organism Structure
2.7.11.14 ATP
-
 Mus musculus