Literature summary extracted from

Hama, K.; Aoki, J.; Fukaya, M.; Kishi, Y.; Sakai, T.; Suzuki, R.; Ohta, H.; Yamori, T.; Watanabe, M.; Chun, J.; Arai, H.
Lysophosphatidic acid and autotaxin stimulate cell motility of neoplastic and non-neoplastic cells through LPA1 (2004), J. Biol. Chem., 279, 17634-17639.

Application

EC Number	Application	Comment	Organism
3.1.4.39	medicine	tumor cell motility-stimulating factor, represents a potential target for cancer therapy	Mus musculus

Inhibitors

EC Number	Inhibitors	Comment	Organism	Structure
3.1.4.39	Ki16425	inhibits the migratory response of lysophosphatidic acid1-expressing cells to both lysophosphatidic acid and ATX	Mus musculus

Organism

EC Number	Organism	UniProt	Comment	Textmining
3.1.4.39	Mus musculus	-	-	-

Source Tissue

EC Number	Source Tissue	Comment	Organism	Textmining
3.1.4.39	skin fibroblast	-	Mus musculus	-

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
3.1.4.39	lysophosphatidylcholine + H2O	-	Mus musculus	lysophosphatidic acid + choline	-	?

Synonyms

EC Number	Synonyms	Comment	Organism
3.1.4.39	ATX	-	Mus musculus
3.1.4.39	autotaxin	-	Mus musculus

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Release 2023.1 (January 2023)