EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
3.4.22.70 | 3,3,3-trifluoro-1-(phenylsulfonyl)-1-propene | IC50: 0.19 mM, irreversible | Staphylococcus aureus | |
3.4.22.70 | cis-1,2-bis(phenylsulfonyl)ethylene | IC50: 0.00113 mM, irreversible | Staphylococcus aureus | |
3.4.22.70 | divinyl sulfone | IC50: 0.00106 mM, irreversible | Staphylococcus aureus | |
3.4.22.70 | ethyl vinyl sulfone | IC50: 0.00471 mM, irreversible | Staphylococcus aureus | |
3.4.22.70 | methyl vinyl sulfone | IC50: 0.00624 mM, irreversible | Staphylococcus aureus | |
3.4.22.70 | additional information | no inhibition by phenyl trans-styryl sulfone | Staphylococcus aureus | |
3.4.22.70 | phenyl vinyl sulfone | IC50: 0.736 mM, irreversible | Staphylococcus aureus |
EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
---|
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
3.4.22.70 | additional information | Staphylococcus aureus | the transpeptidase required for cell wall protein anchoring and virulence in Staphylococcus aureus | ? | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
3.4.22.70 | Staphylococcus aureus | - |
- |
- |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
3.4.22.70 | additional information | the transpeptidase required for cell wall protein anchoring and virulence in Staphylococcus aureus | Staphylococcus aureus | ? | - |
? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
3.4.22.70 | SrtA | - |
Staphylococcus aureus |
EC Number | IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|---|
3.4.22.70 | 0.00106 | - |
IC50: 0.00106 mM, irreversible | Staphylococcus aureus | divinyl sulfone | |
3.4.22.70 | 0.00113 | - |
IC50: 0.00113 mM, irreversible | Staphylococcus aureus | cis-1,2-bis(phenylsulfonyl)ethylene | |
3.4.22.70 | 0.00471 | - |
IC50: 0.00471 mM, irreversible | Staphylococcus aureus | ethyl vinyl sulfone | |
3.4.22.70 | 0.00624 | - |
IC50: 0.00624 mM, irreversible | Staphylococcus aureus | methyl vinyl sulfone | |
3.4.22.70 | 0.19 | - |
IC50: 0.19 mM, irreversible | Staphylococcus aureus | 3,3,3-trifluoro-1-(phenylsulfonyl)-1-propene | |
3.4.22.70 | 0.736 | - |
IC50: 0.736 mM, irreversible | Staphylococcus aureus | phenyl vinyl sulfone |