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Literature summary extracted from

  • Tanaka, M.; Kishi, Y.; Takanezawa, Y.; Kakehi, Y.; Aoki, J.; Arai, H.
    Prostatic acid phosphatase degrades lysophosphatidic acid in seminal plasma (2004), FEBS Lett., 571, 197-204.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.1.3.2 DL-tartrate
-
 Homo sapiens
3.1.3.2 additional information no or poor inhibition by EDTA, L-phenylalanine, homoarginine, and L-leucine Homo sapiens
3.1.3.2 vanadate
-
 Homo sapiens

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
3.1.3.2 extracellular
-
 Homo sapiens
-
-

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
3.1.3.2 additional information
-
 two peaks over a broad range Homo sapiens
3.1.3.2 55000
-
 x * 55000, prostatic enzyme, SDS-PAGE Homo sapiens

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.1.3.2 lysophosphatidic acid + H2O Homo sapiens in seminal plasma mainly 16:0- or 18:0-lysophosphatidic acid monoacylglycerol + phosphate
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
3.1.3.2 Homo sapiens
-
-
-
3.1.4.39 Homo sapiens
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
3.1.3.2 from seminal plasma by anion exchange chromatography and gel filtration Homo sapiens

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.1.3.2 cerebrospinal fluid
-
 Homo sapiens
-
3.1.3.2 prostate gland
-
 Homo sapiens
-
3.1.3.2 seminal plasma two enzyme activities in seminal plasma Homo sapiens
-
3.1.3.2 serum
-
 Homo sapiens
-
3.1.3.2 urine low activity Homo sapiens
-
3.1.4.39 cerebrospinal fluid
-
 Homo sapiens
-
3.1.4.39 seminal plasma
-
 Homo sapiens
-
3.1.4.39 serum
-
 Homo sapiens
-
3.1.4.39 spermatid
-
 Homo sapiens
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
3.1.3.2 additional information
-
-
 Homo sapiens

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.1.3.2 lysophosphatidic acid + H2O
-
 Homo sapiens monoacylglycerol + phosphate
-
 ?
3.1.3.2 lysophosphatidic acid + H2O in seminal plasma mainly 16:0- or 18:0-lysophosphatidic acid Homo sapiens monoacylglycerol + phosphate
-
 ?
3.1.3.2 additional information the prostatic enzyme is non-specific Homo sapiens ?
-
 ?
3.1.4.39 lysophosphatidylcholine + H2O
-
 Homo sapiens lysophosphatidic acid + choline
-
 ?

Subunits

EC Number Subunits Comment Organism
3.1.3.2 ? x * 55000, prostatic enzyme, SDS-PAGE Homo sapiens

Synonyms

EC Number Synonyms Comment Organism
3.1.3.2 LPA-phosphatase
-
 Homo sapiens
3.1.3.2 PAP
-
 Homo sapiens
3.1.3.2 prostatic acid phosphatase
-
 Homo sapiens
3.1.4.39 ATX/NPP2
-
 Homo sapiens
3.1.4.39 autotaxin
-
 Homo sapiens
3.1.4.39 lysophospholipase D
-
 Homo sapiens
3.1.4.39 lysoPLD
-
 Homo sapiens

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
3.1.3.2 37
-
 assay at Homo sapiens

pH Range

EC Number pH Minimum pH Maximum Comment Organism
3.1.3.2 4 7
-
 Homo sapiens