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Literature summary extracted from

  • Schroder, O.; Sjostrom, M.; Qiu, H.; Jakobsson, P.J.; Haeggstrom, J.Z.
    Microsomal glutathione S-transferases: selective up-regulation of leukotriene C4 synthase during lipopolysaccharide-induced pyresis (2005), Cell. Mol. Life Sci., 62, 87-94.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
4.4.1.20 lipopolysaccharide from Escherichia coli serotype O26:B26, increases mRNA expression in heart, brain, liver and adrenal gland Rattus norvegicus

Cloned(Commentary)

EC Number Cloned (Comment) Organism
4.4.1.20
-
Rattus norvegicus

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
4.4.1.20 18000
-
x * 18000, SDS-PAGE Rattus norvegicus

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
4.4.1.20 leukotriene C4 Rattus norvegicus
-
leukotriene A4 + glutathione
-
r

Organism

EC Number Organism UniProt Comment Textmining
4.4.1.20 Rattus norvegicus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
4.4.1.20 adrenal gland
-
Rattus norvegicus
-
4.4.1.20 brain
-
Rattus norvegicus
-
4.4.1.20 colon
-
Rattus norvegicus
-
4.4.1.20 heart
-
Rattus norvegicus
-
4.4.1.20 ileum
-
Rattus norvegicus
-
4.4.1.20 liver
-
Rattus norvegicus
-
4.4.1.20 lung
-
Rattus norvegicus
-
4.4.1.20 skeletal muscle
-
Rattus norvegicus
-
4.4.1.20 spleen
-
Rattus norvegicus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4.4.1.20 leukotriene A4 + glutathione pH 7.4, room temperature Rattus norvegicus leukotriene C4
-
r
4.4.1.20 leukotriene C4
-
Rattus norvegicus leukotriene A4 + glutathione
-
r

Subunits

EC Number Subunits Comment Organism
4.4.1.20 ? x * 18000, SDS-PAGE Rattus norvegicus

Synonyms

EC Number Synonyms Comment Organism
4.4.1.20 leukotriene C4 synthase
-
Rattus norvegicus
4.4.1.20 LTC4S
-
Rattus norvegicus