EC Number | Application | Comment | Organism |
---|---|---|---|
3.4.21.77 | medicine | enzyme may modulate the tumor-associated urokinase-type plasminogen activator/urokinase-type plasminogen activator receptor-system activity by either activating the pro-enzyme form of plasminogen activator or cleaving the cell surface-associated receptor | Homo sapiens |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
3.4.21.B12 | additional information | Homo sapiens | enzyme modulates the tumor-associated urokinase-type plasminogen activator/urokinase-type plasminogen activator receptor system activity by either activating the pro-enzyme form of urokinase-type plasminogen activator or cleaving the cell surface-associated urokinase-type plasminogen activator receptor | ? | - |
? | |
3.4.21.35 | additional information | Homo sapiens | tissue kallikrein 4 regulates the structure and functions of the tumor-associated urokinase-type plasminogen activator receptor | ? | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
3.4.21.B12 | Homo sapiens | - |
- |
- |
3.4.21.35 | Homo sapiens | - |
- |
- |
3.4.21.77 | Homo sapiens | - |
isoform tissue kallikrein 4, hK4 | - |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
3.4.21.B12 | additional information | enzyme modulates the tumor-associated urokinase-type plasminogen activator/urokinase-type plasminogen activator receptor system activity by either activating the pro-enzyme form of urokinase-type plasminogen activator or cleaving the cell surface-associated urokinase-type plasminogen activator receptor | Homo sapiens | ? | - |
? | |
3.4.21.B12 | urokinase-type plasminogen activator receptor + H2 | cleavage occurs in D1-D2 linker sequence and, to a lesser extent, in D3 juxtamembrane domain | Homo sapiens | ? | - |
? | |
3.4.21.35 | additional information | tissue kallikrein 4 regulates the structure and functions of the tumor-associated urokinase-type plasminogen activator receptor | Homo sapiens | ? | - |
? | |
3.4.21.77 | urokinase-type plasminogen activator receptor + H2O | - |
Homo sapiens | ? | cleavage within D1-D2 linker sequence and in its D3 juxtamembrane domain | ? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
3.4.21.35 | tissue kallikrein 4 | - |
Homo sapiens |
3.4.21.77 | K4 | - |
Homo sapiens |