Literature summary extracted from

Oshige, M.; Takeuchi, R.; Ruike, R.; Kuroda, K.; Sakaguchi, K.
Subunit protein-affinity isolation of Drosophila DNA polymerase epsilon catalytic subunit (2004), Protein Expr. Purif., 35, 248-256.

Inhibitors

EC Number	Inhibitors	Comment	Organism	Structure
2.7.7.7	Mn2+	inhibits 3'-5'-proofreading activity, thereby decreasing the fidelity of DNA replication by 50%	Drosophila melanogaster

Metals/Ions

EC Number	Metals/Ions	Comment	Organism	Structure
2.7.7.7	Mg2+	synthesizes DNA processively in the presence of Mn2+ and Mg2+, optimal Mg2+ concentration is 3 mM	Drosophila melanogaster
2.7.7.7	Mn2+	synthesizes DNA processively in the presence of Mn2+ and Mg2+	Drosophila melanogaster

Organism

EC Number	Organism	UniProt	Comment	Textmining
2.7.7.7	Drosophila melanogaster	-	-	-

Purification (Commentary)

EC Number	Purification (Comment)	Organism
2.7.7.7	DNA polymerase epsilon catalytic subunit	Drosophila melanogaster

Specific Activity [micromol/min/mg]

EC Number	Specific Activity Minimum [µmol/min/mg]	Specific Activity Maximum [µmol/min/mg]	Comment	Organism
2.7.7.7	additional information	-	-	Drosophila melanogaster

Synonyms

EC Number	Synonyms	Comment	Organism
2.7.7.7	DNA polymerase epsilon	-	Drosophila melanogaster

pH Optimum

EC Number	pH Optimum Minimum	pH Optimum Maximum	Comment	Organism
2.7.7.7	7.5	-	-	Drosophila melanogaster

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Release 2023.1 (January 2023)