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Literature summary extracted from

  • Beis, K.; Srikannathasan, V.; Liu, H.; Fullerton, S.W.; Bamford, V.A.; Sanders, D.A.; Whitfield, C.; McNeil, M.R.; Naismith, J.H.
    Crystal structures of Mycobacteria tuberculosis and Klebsiella pneumoniae UDP-galactopyranose mutase in the oxidised state and Klebsiella pneumoniae UDP-galactopyranose mutase in the (active) reduced state (2005), J. Mol. Biol., 348, 971-982.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

EC Number Cloned (Comment) Organism
5.4.99.9
-
 Klebsiella pneumoniae
5.4.99.9 expression in Escherichia coli (BL21(DE3)) Mycobacterium tuberculosis

Crystallization (Commentary)

EC Number Crystallization (Comment) Organism
5.4.99.9 in the (active) reduced state, with FAD, crystal structure at 2.2 A resolution, with FADH-, crystal structure at 2.25 A resolution Klebsiella pneumoniae
5.4.99.9 in the oxidized state, with FAD, crystal structure at 2.25 A resolution Mycobacterium tuberculosis

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
5.4.99.9 UDP-D-galactopyranose Klebsiella pneumoniae
-
 UDP-D-galactofuranose
-
 r
5.4.99.9 UDP-D-galactopyranose Mycobacterium tuberculosis
-
 UDP-D-galactofuranose
-
 r

Organism

EC Number Organism UniProt Comment Textmining
5.4.99.9 Klebsiella pneumoniae
-
-
-
5.4.99.9 Mycobacterium tuberculosis
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
5.4.99.9 the recombinant enzyme Klebsiella pneumoniae
5.4.99.9 the recombinant enzyme from Escherichia coli Mycobacterium tuberculosis

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
5.4.99.9 UDP-D-galactopyranose
-
 Klebsiella pneumoniae UDP-D-galactofuranose
-
 r
5.4.99.9 UDP-D-galactopyranose
-
 Mycobacterium tuberculosis UDP-D-galactofuranose
-
 r

Subunits

EC Number Subunits Comment Organism
5.4.99.9 dimer alpha2, crystal structure Klebsiella pneumoniae
5.4.99.9 dimer alpha2, crystal structure Mycobacterium tuberculosis

Synonyms

EC Number Synonyms Comment Organism
5.4.99.9 UDP-galactopyranose mutase
-
 Klebsiella pneumoniae
5.4.99.9 UDP-galactopyranose mutase
-
 Mycobacterium tuberculosis

Cofactor

EC Number Cofactor Comment Organism Structure
5.4.99.9 FAD
-
 Klebsiella pneumoniae
5.4.99.9 FAD
-
 Mycobacterium tuberculosis