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Literature summary extracted from

  • Sato, M.; Kirimura, K.; Kino, K.
    D-Amino acid dipeptide production utilizing D-alanine-D-alanine ligases with novel substrate specificity (2005), J. Biosci. Bioeng., 99, 623-628.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
6.3.2.4 expression in Escherichia coli BL21 Escherichia coli
6.3.2.4 expression in Escherichia coli BL21 Thermotoga maritima
6.3.2.4 expression in Escherichia coli BL21 Synechocystis sp. PCC 6803
6.3.2.4 expression in Escherichia coli BL21 Oceanobacillus iheyensis

Inhibitors

EC Number Inhibitors Comment Organism Structure
6.3.2.4 dipeptides
-
 Escherichia coli
6.3.2.4 dipeptides
-
 Oceanobacillus iheyensis
6.3.2.4 dipeptides
-
 Synechocystis sp. PCC 6803
6.3.2.4 dipeptides
-
 Thermotoga maritima

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
6.3.2.4 ATP + D-alanine Escherichia coli
-
 ADP + phosphate + D-alanyl-D-alanine
-
 ?
6.3.2.4 ATP + D-alanine Thermotoga maritima
-
 ADP + phosphate + D-alanyl-D-alanine
-
 ?
6.3.2.4 ATP + D-alanine Synechocystis sp. PCC 6803
-
 ADP + phosphate + D-alanyl-D-alanine
-
 ?
6.3.2.4 ATP + D-alanine Oceanobacillus iheyensis
-
 ADP + phosphate + D-alanyl-D-alanine
-
 ?
6.3.2.4 ATP + D-alanine Oceanobacillus iheyensis JCM 11309
-
 ADP + phosphate + D-alanyl-D-alanine
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
6.3.2.4 Escherichia coli
-
 K12
-
6.3.2.4 Oceanobacillus iheyensis
-
 JCM 11309
-
6.3.2.4 Oceanobacillus iheyensis JCM 11309
-
 JCM 11309
-
6.3.2.4 Synechocystis sp. PCC 6803
-
-
-
6.3.2.4 Thermotoga maritima
-
 ATCC 43589
-

Purification (Commentary)

EC Number Purification (Comment) Organism
6.3.2.4
-
 Escherichia coli
6.3.2.4
-
 Thermotoga maritima
6.3.2.4
-
 Synechocystis sp. PCC 6803
6.3.2.4
-
 Oceanobacillus iheyensis

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
6.3.2.4 ATP + D-alanine
-
 Escherichia coli ADP + phosphate + D-alanyl-D-alanine
-
 ?
6.3.2.4 ATP + D-alanine
-
 Thermotoga maritima ADP + phosphate + D-alanyl-D-alanine
-
 ?
6.3.2.4 ATP + D-alanine
-
 Synechocystis sp. PCC 6803 ADP + phosphate + D-alanyl-D-alanine
-
 ?
6.3.2.4 ATP + D-alanine
-
 Oceanobacillus iheyensis ADP + phosphate + D-alanyl-D-alanine
-
 ?
6.3.2.4 ATP + D-alanine
-
 Oceanobacillus iheyensis JCM 11309 ADP + phosphate + D-alanyl-D-alanine
-
 ?
6.3.2.4 ATP + D-alanine + D-serine
-
 Escherichia coli ADP + D-alanyl-D-serine + D-alanyl-D-alanine + D-seryl-D-serine
-
 ?
6.3.2.4 ATP + D-alanine + D-serine
-
 Thermotoga maritima ADP + D-alanyl-D-serine + D-alanyl-D-alanine + D-seryl-D-serine
-
 ?
6.3.2.4 ATP + D-alanine + D-serine
-
 Synechocystis sp. PCC 6803 ADP + D-alanyl-D-serine + D-alanyl-D-alanine + D-seryl-D-serine
-
 ?
6.3.2.4 D-cysteine + ATP
-
 Escherichia coli ADP + D-cysteinyl-D-cysteine
-
 ?
6.3.2.4 D-cysteine + ATP
-
 Thermotoga maritima ADP + D-cysteinyl-D-cysteine
-
 ?
6.3.2.4 D-cysteine + ATP
-
 Synechocystis sp. PCC 6803 ADP + D-cysteinyl-D-cysteine
-
 ?
6.3.2.4 D-serine + ATP
-
 Escherichia coli ADP + D-serinyl-D-serine
-
 ?
6.3.2.4 D-serine + ATP
-
 Thermotoga maritima ADP + D-serinyl-D-serine
-
 ?
6.3.2.4 D-serine + ATP
-
 Synechocystis sp. PCC 6803 ADP + D-serinyl-D-serine
-
 ?
6.3.2.4 D-threonine + ATP
-
 Escherichia coli ADP + D-threonyl-D-threonine
-
 ?
6.3.2.4 D-threonine + ATP
-
 Thermotoga maritima ADP + D-threonyl-D-threonine
-
 ?
6.3.2.4 D-threonine + ATP
-
 Synechocystis sp. PCC 6803 ADP + D-threonyl-D-threonine
-
 ?
6.3.2.4 dipeptides + ATP
-
 Escherichia coli ?
-
 ?
6.3.2.4 dipeptides + ATP
-
 Thermotoga maritima ?
-
 ?
6.3.2.4 dipeptides + ATP
-
 Synechocystis sp. PCC 6803 ?
-
 ?
6.3.2.4 dipeptides + ATP
-
 Oceanobacillus iheyensis ?
-
 ?
6.3.2.4 dipeptides + ATP
-
 Oceanobacillus iheyensis JCM 11309 ?
-
 ?
6.3.2.4 glycine + glycine + ATP
-
 Escherichia coli ADP + Gly-Gly + phosphate
-
 ?
6.3.2.4 glycine + glycine + ATP
-
 Thermotoga maritima ADP + Gly-Gly + phosphate
-
 ?
6.3.2.4 glycine + glycine + ATP
-
 Synechocystis sp. PCC 6803 ADP + Gly-Gly + phosphate
-
 ?

Synonyms

EC Number Synonyms Comment Organism
6.3.2.4 Ddl
-
 Escherichia coli
6.3.2.4 Ddl
-
 Thermotoga maritima
6.3.2.4 Ddl
-
 Synechocystis sp. PCC 6803
6.3.2.4 Ddl
-
 Oceanobacillus iheyensis