EC Number | General Stability | Organism |
---|---|---|
2.6.1.57 | aromatic aminotransferase AT-1 is unstable to freeze-thaw treatment. With a single freeze-thaw cycle the enzyme loses about 50% of its original activity. Additional freeze-thaw treatments completely inactivate AT-1 | Pseudomonas aeruginosa |
2.6.1.57 | aromatic aminotransferase AT-2 is stable to repeated freeze-thaw treatments | Pseudomonas aeruginosa |
EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|---|
2.6.1.57 | 64000 | - |
aromatic aminotransferase AT-1, gel filtration | Pseudomonas aeruginosa |
2.6.1.57 | 64000 | - |
aromatic aminotransferase AT-2, gel filtration | Pseudomonas aeruginosa |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.6.1.57 | additional information | Pseudomonas aeruginosa | role of enzyme AT-2 in L-Phe and L-Tyr biosynthesis | ? | - |
? | |
2.6.1.57 | additional information | Pseudomonas aeruginosa | the enzyme AT-1 must primarily be engaged in L-aspartate and L-glutamate synthesis | ? | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
2.6.1.57 | Pseudomonas aeruginosa | - |
aromatic aminotransferase AT-1 | - |
2.6.1.57 | Pseudomonas aeruginosa | - |
aromatic aminotransferase AT-2 | - |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.6.1.57 | 2-oxoglutarate + Asp | aromatic aminotransferase AT-1 | Pseudomonas aeruginosa | L-glutamate + 2-oxosuccinic acid | - |
? | |
2.6.1.57 | 2-oxoglutarate + Asp | aromatic aminotransferase AT-2 | Pseudomonas aeruginosa | L-glutamate + 2-oxosuccinic acid | - |
? | |
2.6.1.57 | 2-oxoglutarate + Glu | aromatic aminotransferase AT-1 | Pseudomonas aeruginosa | Glu + 2-oxoglutarate | - |
? | |
2.6.1.57 | 2-oxoglutarate + Glu | aromatic aminotransferase AT-2 | Pseudomonas aeruginosa | Glu + 2-oxoglutarate | - |
? | |
2.6.1.57 | 2-oxoglutarate + L-Phe | aromatic aminotransferase AT-1 | Pseudomonas aeruginosa | L-Glu + phenylpyruvate | - |
? | |
2.6.1.57 | 2-oxoglutarate + L-Phe | aromatic aminotransferase AT-2 | Pseudomonas aeruginosa | L-Glu + phenylpyruvate | - |
? | |
2.6.1.57 | 2-oxoglutarate + Tyr | aromatic aminotransferase AT-1 | Pseudomonas aeruginosa | L-glutamate + 4-hydroxyphenylpyruvate | - |
? | |
2.6.1.57 | 2-oxoglutarate + Tyr | aromatic aminotransferase AT-2 | Pseudomonas aeruginosa | L-glutamate + 4-hydroxyphenylpyruvate | - |
? | |
2.6.1.57 | 4-hydroxyphenylpyruvate + Asp | aromatic aminotransferase AT-1 | Pseudomonas aeruginosa | Tyr + 2-oxosuccinate | - |
? | |
2.6.1.57 | 4-hydroxyphenylpyruvate + Asp | aromatic aminotransferase AT-2 | Pseudomonas aeruginosa | Tyr + 2-oxosuccinate | - |
? | |
2.6.1.57 | 4-hydroxyphenylpyruvate + Glu | aromatic aminotransferase AT-1 | Pseudomonas aeruginosa | Tyr + 2-oxoglutarate | - |
? | |
2.6.1.57 | 4-hydroxyphenylpyruvate + Glu | aromatic aminotransferase AT-2 | Pseudomonas aeruginosa | Tyr + 2-oxoglutarate | - |
? | |
2.6.1.57 | 4-hydroxyphenylpyruvate + Phe | aromatic aminotransferase AT-1 | Pseudomonas aeruginosa | tyr + phenylpyruvate | - |
? | |
2.6.1.57 | 4-hydroxyphenylpyruvate + Phe | aromatic aminotransferase AT-2 | Pseudomonas aeruginosa | tyr + phenylpyruvate | - |
? | |
2.6.1.57 | 4-hydroxyphenylpyruvate + Tyr | aromatic aminotransferase AT-1 | Pseudomonas aeruginosa | Tyr + 4-hydroxyphenylpyruvate | - |
? | |
2.6.1.57 | 4-hydroxyphenylpyruvate + Tyr | aromatic aminotransferase AT-2 | Pseudomonas aeruginosa | Tyr + 4-hydroxyphenylpyruvate | - |
? | |
2.6.1.57 | additional information | role of enzyme AT-2 in L-Phe and L-Tyr biosynthesis | Pseudomonas aeruginosa | ? | - |
? | |
2.6.1.57 | additional information | the enzyme AT-1 must primarily be engaged in L-aspartate and L-glutamate synthesis | Pseudomonas aeruginosa | ? | - |
? | |
2.6.1.57 | oxaloacetate + Asp | aromatic aminotransferase AT-1 | Pseudomonas aeruginosa | Asp + oxaloacetate | - |
? | |
2.6.1.57 | oxaloacetate + Asp | aromatic aminotransferase AT-2 | Pseudomonas aeruginosa | Asp + oxaloacetate | - |
? | |
2.6.1.57 | oxaloacetate + Glu | aromatic aminotransferase AT-1 | Pseudomonas aeruginosa | Asp + 2-oxoglutarate | - |
? | |
2.6.1.57 | oxaloacetate + Glu | aromatic aminotransferase AT-2 | Pseudomonas aeruginosa | Asp + 2-oxoglutarate | - |
? | |
2.6.1.57 | oxaloacetate + Phe | aromatic aminotransferase AT-1 | Pseudomonas aeruginosa | Asp + phenylpyruvate | - |
? | |
2.6.1.57 | oxaloacetate + Phe | aromatic aminotransferase AT-2 | Pseudomonas aeruginosa | Asp + phenylpyruvate | - |
? | |
2.6.1.57 | oxaloacetate + Tyr | aromatic aminotransferase AT-1 | Pseudomonas aeruginosa | Asp + 4-hydroxyphenylpyruvate | - |
? | |
2.6.1.57 | oxaloacetate + Tyr | aromatic aminotransferase AT-2 | Pseudomonas aeruginosa | Asp + 4-hydroxyphenylpyruvate | - |
? | |
2.6.1.57 | phenylpyruvate + Asp | aromatic aminotransferase AT-1 | Pseudomonas aeruginosa | Phe + 2-oxosuccinate | - |
? | |
2.6.1.57 | phenylpyruvate + Asp | aromatic aminotransferase AT-2 | Pseudomonas aeruginosa | Phe + 2-oxosuccinate | - |
? | |
2.6.1.57 | phenylpyruvate + Glu | aromatic aminotransferase AT-1 | Pseudomonas aeruginosa | Phe + 2-oxoglutarate | - |
? | |
2.6.1.57 | phenylpyruvate + Glu | aromatic aminotransferase AT-2 | Pseudomonas aeruginosa | Phe + 2-oxoglutarate | - |
? | |
2.6.1.57 | phenylpyruvate + Phe | aromatic aminotransferase AT-1 | Pseudomonas aeruginosa | Phe + phenylpyruvate | - |
? | |
2.6.1.57 | phenylpyruvate + Phe | aromatic aminotransferase AT-2 | Pseudomonas aeruginosa | Phe + phenylpyruvate | - |
? | |
2.6.1.57 | phenylpyruvate + Tyr | aromatic aminotransferase AT-1 | Pseudomonas aeruginosa | Phe + 3-(4-hydroxyphenyl)-2-oxopropanoic acid | - |
? | |
2.6.1.57 | phenylpyruvate + Tyr | aromatic aminotransferase AT-2 | Pseudomonas aeruginosa | Phe + 3-(4-hydroxyphenyl)-2-oxopropanoic acid | - |
? | |
2.6.1.57 | prephenate + Asp | aromatic aminotransferase AT-1 | Pseudomonas aeruginosa | arogenate + 2-oxosuccinate | - |
? | |
2.6.1.57 | prephenate + Asp | aromatic aminotransferase AT-2 | Pseudomonas aeruginosa | arogenate + 2-oxosuccinate | - |
? | |
2.6.1.57 | prephenate + Glu | aromatic aminotransferase AT-1 | Pseudomonas aeruginosa | arogenate + 2-oxoglutarate | - |
? | |
2.6.1.57 | prephenate + Glu | aromatic aminotransferase AT-2 | Pseudomonas aeruginosa | arogenate + 2-oxoglutarate | - |
? | |
2.6.1.57 | prephenate + Phe | aromatic aminotransferase AT-1 | Pseudomonas aeruginosa | arogenate + phenylpyruvate | - |
? | |
2.6.1.57 | prephenate + Phe | aromatic aminotransferase AT-2 | Pseudomonas aeruginosa | arogenate + phenylpyruvate | - |
? | |
2.6.1.57 | prephenate + Tyr | aromatic aminotransferase AT-1 | Pseudomonas aeruginosa | arogenate + 4-hydroxyphenylpyruvate | - |
? | |
2.6.1.57 | prephenate + Tyr | aromatic aminotransferase AT-2 | Pseudomonas aeruginosa | arogenate + 4-hydroxyphenylpyruvate | - |
? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
2.6.1.57 | aromatic aminotransferase AT-1 | - |
Pseudomonas aeruginosa |
2.6.1.57 | aromatic aminotransferase AT-2 | - |
Pseudomonas aeruginosa |
2.6.1.57 | AT-1 | - |
Pseudomonas aeruginosa |
2.6.1.57 | AT-2 | - |
Pseudomonas aeruginosa |
EC Number | Temperature Stability Minimum [°C] | Temperature Stability Maximum [°C] | Comment | Organism |
---|---|---|---|---|
2.6.1.57 | 60 | - |
inactivated at, aromatic aminotransferase AT-1 loses activity much more precipitously than does aromatic aminotransferase AT-2 | Pseudomonas aeruginosa |
EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|---|
2.6.1.57 | 6.2 | - |
L-glutamate, aromatic aminotransferase AT-1 | Pseudomonas aeruginosa |
2.6.1.57 | 7 | - |
L-Phe, L-Tyr, L-Asp or L-Glu as substrate, aromatic aminotransferase AT-2 | Pseudomonas aeruginosa |
2.6.1.57 | 7.6 | - |
L-Asp, aromatic aminotransferase AT-1 | Pseudomonas aeruginosa |
2.6.1.57 | 8.4 | - |
L-Phe or L-Tyr, aromatic aminotransferase AT-1 | Pseudomonas aeruginosa |