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Literature summary extracted from

  • Poole, D.P.; Hunne, B.; Robbins, H.L.; Furness, J.B.
    Protein kinase C isoforms in the enteric nervous system (2003), Histochem. Cell Biol., 120, 51-61.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
2.7.11.13 anionic phospholipids isozymes alpha, betaI, betaII, and gamma require anionic phospholipids for activity, isozymes delta, epsilon, eta, and theta do not Cavia porcellus
2.7.11.13 diacylglycerol isozymes alpha, betaI, betaII, and gamma require diacylglycerol for activity, isozymes delta, epsilon, eta, and theta do not Cavia porcellus
2.7.11.13 additional information the isozymes show varying activation requirements Cavia porcellus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.7.11.13 cytoplasm isozymes beta, gamma, delta, epsilon Cavia porcellus 5737
-
2.7.11.13 additional information no isozyme delta in the nucleus Cavia porcellus
-
-

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
2.7.11.13 Ca2+ isozymes alpha, betaI, betaII, and gamma require Ca2+ for activity, isozymes delta, epsilon, eta, and theta do not Cavia porcellus

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.7.11.13 additional information Cavia porcellus the enzyme is essential for transduction of signals in a wide range of cell types, including neurons ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.7.11.13 Cavia porcellus
-
 female and male, several isozymes
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.7.11.13 capillary isozyme gamma Cavia porcellus
-
2.7.11.13 duodenum isozymes gamma, and epsilon Cavia porcellus
-
2.7.11.13 endothelial cell isozyme gamma Cavia porcellus
-
2.7.11.13 enteric nervous system several isozymes Cavia porcellus
-
2.7.11.13 fibroblast isozyme beta Cavia porcellus
-
2.7.11.13 glial cell glial network Cavia porcellus
-
2.7.11.13 ileum myenteric neurons, isozymes gamma, lambda, and epsilon Cavia porcellus
-
2.7.11.13 lymph vessel isozyme gamma Cavia porcellus
-
2.7.11.13 additional information tissue- and cell-type-specific expression of isozymes, overview, involved in regulation of organ, e.g. intestinal, function Cavia porcellus
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2.7.11.13 myenteron myenteric neuron, isozyme beta in submucosal ganglia of neurons, isozymes gamma, eta, and theta are present in intrinsic primary afferent neurons, but not in other myenteric neurons, low expression of isozyme alpha, isozyme epsilon Cavia porcellus
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2.7.11.13 small intestine myenteric neurons Cavia porcellus
-
2.7.11.13 smooth muscle no isozyme beta, high expression of isozyme delta Cavia porcellus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.11.13 additional information the enzyme is essential for transduction of signals in a wide range of cell types, including neurons Cavia porcellus ?
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.7.11.13 PKC
-
 Cavia porcellus