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Literature summary extracted from

  • de Jong, L.; Meng, Y.; Dent, J.; Hekimi, S.
    Thiamine pyrophosphate biosynthesis and transport in the nematode Caenorhabditis elegans (2004), Genetics, 168, 845-854.
    View publication on PubMed

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.7.6.2 ATP + thiamine Caenorhabditis elegans the tpk-1 gene functions cell nonautonomously, as the expression of wild-type tpk-1 in one tissue can residue the function of other tissues that express only mutant tpk-1. Thiamine diphosphate can be transported across the cell membrane AMP + thiamine diphosphate
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Organism

EC Number Organism UniProt Comment Textmining
2.7.6.2 Caenorhabditis elegans P30636
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Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.6.2 ATP + thiamine the tpk-1 gene functions cell nonautonomously, as the expression of wild-type tpk-1 in one tissue can residue the function of other tissues that express only mutant tpk-1. Thiamine diphosphate can be transported across the cell membrane Caenorhabditis elegans AMP + thiamine diphosphate
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 ?

Synonyms

EC Number Synonyms Comment Organism
2.7.6.2 thiamine pyrophosphokinase encoded by tpk-1 Caenorhabditis elegans