EC Number | Activating Compound | Comment | Organism | Structure |
---|---|---|---|---|
2.7.10.2 | H2O2 | increases tyrosine phosphorylation in vivo, genistein decreases the activating effect | Oncorhynchus mykiss |
EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
2.7.10.2 | genistein | - |
Oncorhynchus mykiss |
EC Number | Metals/Ions | Comment | Organism | Structure |
---|---|---|---|---|
2.7.10.2 | Cu2+ | increases tyrosine phosphorylation in vivo, prevented by preincubation with genistein | Oncorhynchus mykiss | |
2.7.10.2 | Hg2+ | increases tyrosine phosphorylation in vivo, genistein decreases the activating effect | Oncorhynchus mykiss |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.7.10.2 | ATP + a [protein]-L-tyrosine | Oncorhynchus mykiss | - |
ADP + a [protein]-L-tyrosine phosphate | - |
? | |
2.7.10.2 | additional information | Oncorhynchus mykiss | enzyme is involved in cell growth, differentiation, and apoptosis | ? | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
2.7.10.2 | Oncorhynchus mykiss | - |
- |
- |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
2.7.10.2 | hepatoma cell | - |
Oncorhynchus mykiss | - |
2.7.10.2 | RTH-149 cell | hepatoma cell line | Oncorhynchus mykiss | - |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.7.10.2 | ATP + a [protein]-L-tyrosine | - |
Oncorhynchus mykiss | ADP + a [protein]-L-tyrosine phosphate | - |
? | |
2.7.10.2 | additional information | enzyme is involved in cell growth, differentiation, and apoptosis | Oncorhynchus mykiss | ? | - |
? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
2.7.10.2 | non-receptor tyrosine kinase | - |
Oncorhynchus mykiss |