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Literature summary extracted from
- 1,4-Anhydrogalactopyranose is not an intermediate of the mutase catalyzed UDP-galactopyranose/furanose interconversion (2006), Bioorg. Med. Chem. Lett., 16, 1123-1125.
Inhibitors
| EC Number | Inhibitors | Comment | Organism | Structure |
|---|---|---|---|---|
| 5.4.99.9 | additional information | fluorinated substrate analogues under non-reducing conditions | Mycobacterium tuberculosis | |
| 5.4.99.9 | UDP | - |
Mycobacterium tuberculosis |  |
KM Value [mM]
| EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|---|
| 5.4.99.9 | 0.02 | - |
UDP-galactofuranose | under reducing conditions | Mycobacterium tuberculosis | |
| 5.4.99.9 | 0.19 | - |
UDP-galactofuranose | under non-reducing (native) conditions | Mycobacterium tuberculosis | |
Natural Substrates/ Products (Substrates)
| EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 5.4.99.9 | UDP-galactopyranose | Mycobacterium tuberculosis | essential step of mycobacterial cell wall biosynthesis | UDP-galactofuranose | - |
r | |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 5.4.99.9 | Mycobacterium tuberculosis | - |
- |
- |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 5.4.99.9 | additional information | 1,4-anhydrogalactopyranose does not react with UGM and UDP to form UDP-galactopyranose or UDP-galactofuranose | Mycobacterium tuberculosis | ? | - |
? | |
| 5.4.99.9 | UDP-galactopyranose | - |
Mycobacterium tuberculosis | UDP-galactofuranose | - |
r | |
| 5.4.99.9 | UDP-galactopyranose | essential step of mycobacterial cell wall biosynthesis | Mycobacterium tuberculosis | UDP-galactofuranose | - |
r | |
Synonyms
| EC Number | Synonyms | Comment | Organism |
|---|---|---|---|
| 5.4.99.9 | UDP-galactopyranose mutase | - |
Mycobacterium tuberculosis |
| 5.4.99.9 | UGM | - |
Mycobacterium tuberculosis |
Cofactor
| EC Number | Cofactor | Comment | Organism | Structure |
|---|---|---|---|---|
| 5.4.99.9 | FAD | - |
Mycobacterium tuberculosis | |
Ki Value [mM]
| EC Number | Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
|---|---|---|---|---|---|---|
| 5.4.99.9 | 0.2 | - |
UDP | - |
Mycobacterium tuberculosis | |
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Release 2023.1 (January 2023)
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