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Literature summary extracted from

  • Sakano, Y.; Mutsuga, M.; Tanaka, R.; Suganuma, H.; Inakuma, T.; Toyoda, M.; Goda, Y.; Shibuya, M.; Ebizuka, Y.
    Inhibition of human lanosterol synthase by the constituents of Colocasia esculenta (taro) (2005), Biol. Pharm. Bull., 28, 299-304.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
5.4.99.7 expression in Saccharomyces cerevisiae Homo sapiens

Inhibitors

EC Number Inhibitors Comment Organism Structure
5.4.99.7 ethanol extract from Angelica keiskei leaves 11% inhibition at 0.3 mg/ml Homo sapiens
5.4.99.7 ethanol extract from Basella rubra leaves 5% inhibition at 0.3 mg/ml Homo sapiens
5.4.99.7 ethanol extract from Chrysanthemum morifolium flowers 13% inhibition at 0.3 mg/ml Homo sapiens
5.4.99.7 ethanol extract from Chrysanthemum morifolium leaves 7% inhibition at 0.3 mg/ml Homo sapiens
5.4.99.7 ethanol extract from Colocasia esculenta rhizomes 55% inhibition at 0.3 mg/ml Homo sapiens
5.4.99.7 ethanol extract from Cryptotaenia japonica leaves 10% inhibition at 0.3 mg/ml Homo sapiens
5.4.99.7 ethanol extract from Glycine max immature seeds 14% inhibition at 0.3 mg/ml Homo sapiens
5.4.99.7 ethanol extract from Oenanthe stolonifera leaves 13% inhibition at 0.3 mg/ml Homo sapiens
5.4.99.7 ethanol extract from Perilla frutescens leaves 5% inhibition at 0.3 mg/ml Homo sapiens
5.4.99.7 ethanol extract from Petasites japonicus buds 6% inhibition at 0.3 mg/ml Homo sapiens
5.4.99.7 ethanol extract from Zingiber officinale buds 14% inhibition at 0.3 mg/ml Homo sapiens
5.4.99.7 ethanol extract from Zingiber officinale rhizomes 6% inhibition at 0.3 mg/ml Homo sapiens

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
5.4.99.7 (3S)-2,3-oxidosqualene Homo sapiens
-
 lanosterol
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
5.4.99.7 Homo sapiens
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
5.4.99.7
-
 Homo sapiens

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
5.4.99.7 (3S)-2,3-oxidosqualene
-
 Homo sapiens lanosterol
-
 ?

Synonyms

EC Number Synonyms Comment Organism
5.4.99.7 lanosterol synthase
-
 Homo sapiens
5.4.99.7 OSC
-
 Homo sapiens