EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|---|
4.1.1.64 | 2 | - |
2-aminoisobutanoate | activated by K+ | Burkholderia cepacia | |
4.1.1.64 | 2.2 | - |
2-aminoisobutanoate | activated by Rb+ | Burkholderia cepacia | |
4.1.1.64 | 4.4 | - |
2-aminoisobutanoate | activated by NH4+ | Burkholderia cepacia | |
4.1.1.64 | 5.8 | - |
2-aminoisobutanoate | activated by Mg2+ | Burkholderia cepacia | |
4.1.1.64 | 6.6 | - |
2-aminoisobutanoate | activated by Tl+ | Burkholderia cepacia | |
4.1.1.64 | 7.3 | - |
2-aminoisobutanoate | activated by Cs+ | Burkholderia cepacia | |
4.1.1.64 | 11 | - |
2-aminoisobutanoate | activated by Li+ | Burkholderia cepacia | |
4.1.1.64 | 13 | - |
2-aminoisobutanoate | activated by Na+ | Burkholderia cepacia | |
4.1.1.64 | 18 | - |
2-aminoisobutanoate | activated by Ca2+ | Burkholderia cepacia | |
4.1.1.64 | 66 | - |
2-aminoisobutanoate | activated by Ba2+ | Burkholderia cepacia |
EC Number | Metals/Ions | Comment | Organism | Structure |
---|---|---|---|---|
4.1.1.64 | Ba2+ | gives 10fold lower activity compared to monovalent alkali cations of similar ionic radius, increases association of pyridoxal 5'-phosphate and decreases dissociation rate constant of pyridoxal 5'-phosphate | Burkholderia cepacia | |
4.1.1.64 | Ca2+ | gives 10fold lower activity compared to monovalent alkali cations of similar ionic radius | Burkholderia cepacia | |
4.1.1.64 | Cs+ | activates to a lesser extent than K+ | Burkholderia cepacia | |
4.1.1.64 | K+ | activity is dependent on cations. K+ is the monovalent cation with the optimal size for catalytic activity, increases association of pyridoxal 5'-phosphate and decreases dissociation rate constant of pyridoxal 5'-phosphate | Burkholderia cepacia | |
4.1.1.64 | Li+ | activates to a lesser extent than K+ | Burkholderia cepacia | |
4.1.1.64 | Mg2+ | gives 10fold lower activity compared to monovalent alkali cations of similar ionic radius | Burkholderia cepacia | |
4.1.1.64 | Na+ | activates to a lesser extent than K+, increases association of pyridoxal 5'-phosphate and decreases dissociation rate constant of pyridoxal 5'-phosphate | Burkholderia cepacia | |
4.1.1.64 | NH4+ | activates to a lesser extent than K+ | Burkholderia cepacia | |
4.1.1.64 | Rb+ | activates to a lesser extent than K+ | Burkholderia cepacia | |
4.1.1.64 | Tl+ | activates to a lesser extent than K+ | Burkholderia cepacia |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
4.1.1.64 | Burkholderia cepacia | - |
- |
- |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
4.1.1.64 | 2-Aminoisobutanoate + pyruvate | - |
Burkholderia cepacia | L-Ala + acetone + CO2 | - |
? |
EC Number | Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|---|
4.1.1.64 | 0.05 | - |
2-aminoisobutanoate | activated by Ca2+ | Burkholderia cepacia | |
4.1.1.64 | 0.076 | - |
2-aminoisobutanoate | activated by Mg2+ | Burkholderia cepacia | |
4.1.1.64 | 0.86 | - |
2-aminoisobutanoate | activated by Li+ | Burkholderia cepacia | |
4.1.1.64 | 1.4 | - |
2-aminoisobutanoate | activated by Ba2+ | Burkholderia cepacia | |
4.1.1.64 | 1.83 | - |
2-aminoisobutanoate | activated by Na+ | Burkholderia cepacia | |
4.1.1.64 | 3.8 | - |
2-aminoisobutanoate | activated by Cs+ | Burkholderia cepacia | |
4.1.1.64 | 4.9 | - |
2-aminoisobutanoate | activated by NH4+ | Burkholderia cepacia | |
4.1.1.64 | 5.22 | - |
2-aminoisobutanoate | activated by Tl+ | Burkholderia cepacia | |
4.1.1.64 | 7.4 | - |
2-aminoisobutanoate | activated by Rb+ | Burkholderia cepacia | |
4.1.1.64 | 10.4 | - |
2-aminoisobutanoate | activated by K+ | Burkholderia cepacia |
EC Number | Cofactor | Comment | Organism | Structure |
---|---|---|---|---|
4.1.1.64 | pyridoxal 5'-phosphate | dependent on | Burkholderia cepacia |